73 citations,
July 2013 in “The Journal of Sexual Medicine” Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.
61 citations,
April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
59 citations,
November 2018 in “Psychoneuroendocrinology” Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
36 citations,
June 2001 in “Neuroscience Letters” Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.
34 citations,
November 2017 in “Gynecological Endocrinology” A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.
32 citations,
May 2010 in “Pharmacopsychiatry” Finasteride reduces new brain cells in male mice, possibly causing depression.
30 citations,
May 2019 in “Scientific Reports” Late pregnancy helps repair brain damage in rats due to the GABAergic system.
29 citations,
January 2021 in “Journal of nanobiotechnology” Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.
25 citations,
June 2017 in “Neuropharmacology” Increasing TSPO in the brain reduces anxiety and depression.
21 citations,
October 2018 in “European Journal of Pharmacology” Chemotherapy can cause brain inflammation and damage, and understanding this process could help manage side effects.
14 citations,
October 2016 in “Psychoneuroendocrinology” Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
14 citations,
May 2008 in “Journal of proteome research” Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.
12 citations,
May 2019 in “Molecular Medicine Reports” Forsythiaside A helps reduce brain damage from lack of blood flow by activating certain protective pathways.
11 citations,
November 2021 in “International journal of molecular sciences” Gut microbes significantly affect brain steroid levels.
7 citations,
March 2018 in “Psychiatry and Clinical Psychopharmacology” Valproate can cause brain swelling with high ammonia levels, possibly underreported, especially in psychiatric patients.
3 citations,
January 2022 in “Journal of neuroendocrinology” Sex hormones affect brain cells differently in males and females.
3 citations,
July 2018 in “Biomedicine & pharmacotherapy” Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.
2 citations,
June 2018 in “Physiology & behavior” Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.
1 citations,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.
1 citations,
January 2018 in “The Open Dermatology Journal” Spironolactone may cause increased brain pressure in some patients.
1 citations,
March 2016 in “Neurotoxicity Research” Finasteride may protect brain and improve behavior in rats with liver failure.
Recognizing unusual brain and skin symptoms is crucial for diagnosing lupus early.
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Cannabidivarin (CBDV) helps new brain cells grow and develop in a specific brain area through a certain receptor.
December 2020 in “Innovation in aging” Rapamycin treatment helps reduce brain inflammation and symptoms of mitochondrial disease by blocking specific pathways in mice.
January 2020 in “Nihon Yakuri Gakkai nenkai yoshishu” Minoxidil protects brain tissue directly, not by lowering blood pressure.
January 2018 in “日本薬理学会年会要旨集 =” Minoxidil may protect the brain from damage by preventing cell death and energy loss.
March 2014 in “Human Physiology” DHEA improved brain function and behavior in old monkeys and had additional health benefits.
142 citations,
January 2019 in “Frontiers in Neuroendocrinology” Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.
123 citations,
December 2015 in “Journal of Neuroendocrinology” New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
47 citations,
December 2002 in “Journal of Neurochemistry” Progesterone boosts alcohol's effect on brain, finasteride counters it.