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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

Skin fat helps with body temperature control and has other active roles in health.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Kawasaki Disease is rare and often missed in adults, who show different symptoms than children, and may benefit from early treatment.

Skin has specialized touch receptors that can tell different sensations apart.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

The HR protein's role as a repressor is essential for controlling hair growth.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Advanced human skin models improve drug development and could replace animal testing.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

Light can turn on hair growth cells through a nerve path starting in the eyes.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.