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Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.

PRP therapy may effectively treat hair loss, but more research needed.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.

Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

FOXN1 gene variants cause low T cells and immune issues from birth.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.

Chemotherapy often causes patterned hair loss, with some scalp areas more resistant to hair loss than others.

The document suggests a possible link between Crohn's disease and Johne's disease and calls for more research.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

The CLASI is a reliable tool for measuring the severity of cutaneous lupus erythematosus.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Human hair's ability to get wet is complex and can change with treatments, damage, and environment.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.

Hair loss is more common in men aged 18-49 and increases with age.

Artificially inducing hair regrowth in mice can change the normal pattern and timing of hair growth, with minimal color differences between old and new fur.

Some people experienced hair loss after mesotherapy treatments for hair loss.

The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.

Older age, higher BMI, and family history of diabetes increase the risk of gestational diabetes in pregnant women.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.