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Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

miR-181a-5p helps hair growth by activating a specific signaling pathway.

Cornu cervi pantotrichum pharmacopuncture solution helps mice grow hair by increasing hair follicle cell growth and a growth factor important for hair development.

The WIF1 gene is crucial for hair growth in Angora rabbits.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.

Aging in men is influenced by genetics and lifestyle, leading to muscle loss, bone issues, and skin damage.

Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Skin changes like hair loss, white patches, and nail changes are common in children after bone marrow transplants, often linked to chronic rejection.

Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.

Dates may improve heart health, fight infections, protect kidneys, reduce inflammation, support pregnancy, promote dental and bone health, enhance mental function, and have anti-cancer properties, and are also beneficial for skin and hair care.

A new medical syndrome may include skin changes, hair loss, sweating issues, bone malformations, leg swelling, and low cortisol.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

Zinc is essential for many body functions and imbalances can lead to health problems.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Researchers found certain genes are overactive and others are underactive in men with early balding, which could help create new treatments.

Organ transplant recipients have a higher risk of skin cancer over time, atopic dermatitis skin shows unusual bacterial and fungal patterns, a new tool for measuring hidradenitis suppurativa severity was created, and gene expression changes in male baldness suggest new treatments.