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More East Asians are accepting and getting facial plastic surgery, with a focus on natural-looking results and using both surgical and nonsurgical methods.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The document concludes that transsexual individuals often experience improved quality of life after transitioning, despite higher risks of psychiatric issues and mortality.

Pregnancy can cause skin changes and conditions that need correct diagnosis and treatment for the health of the mother and baby.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Targeted cancer therapies often cause serious skin problems that need careful management.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Adrenal disorders can cause lasting brain and behavior issues in children.

Testosterone may help increase sexual events for women with low libido due to antidepressants.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.