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The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Knuckle Acanthosis Nigricans is common in Latin American youth and may indicate early insulin resistance, especially in those with normal weight.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

Adding licorice gel to laser treatment is more effective for reducing facial hair than laser alone.

The study concluded that a higher waist-hip ratio significantly increases the risk of metabolic syndrome in women with PCOS.

Aging men face unique health issues like erectile dysfunction, prostate problems, and baldness.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.

Selenium supplements can help improve symptoms and metabolic markers in lupus patients.

Isoflavone may help manage PCOS symptoms, but its effectiveness is uncertain.

Herbal treatments can help manage PCOS symptoms.

Dianabol boosts muscle growth but has serious health risks and legal issues.

Ficus racemosa leaf extracts help heal diabetic wounds and lower blood sugar.

Medicinal plants in nutricosmetics contain compounds that can improve skin and hair health.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

PCOS is a common condition in women that can lead to infertility and other health issues, and it's diagnosed by specific criteria with various treatment options available.

Seborrheic dermatitis is influenced by diet, genetics, and psychological factors.

The document concludes that managing PCOS involves lifestyle changes, medication, and monitoring for associated health risks.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.

Smoking doubles the risk of blindness, and physical exercise helps dyslexic children read better.

Dermal stem cells help regenerate hair follicles and heal skin wounds.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.