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The intensive conventional diet with exercise led to better long-term weight loss and health improvements than the very low calorie diet in obese type 2 diabetics.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Vegetarian Indian women with PCOS have higher inflammation levels than non-vegetarians.

The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Rosiglitazone may be better than metformin for insulin resistance in PCOS, but more research is needed on certain biomarkers.

The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.

Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.

Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.

Type 2 diabetes may increase the risk of severe hair loss in African American women.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Women with polycystic ovary syndrome have a higher risk of certain fractures.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.

We need better ways to test and understand SARMs to make safer and more effective treatments.