18 citations,
March 2015 in “Journal of Investigative Dermatology” Silencing certain circadian clock genes increases skin pigmentation.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
30 citations,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
3 citations,
January 2023 in “International Journal of Molecular Sciences” Heat Shock Proteins are important in the development of Polycystic Ovarian Syndrome and could be targets for new treatments.
38 citations,
August 2012 in “Biochemical and biophysical research communications” Human leukocytes and beard hair follicle cells have internal daily clocks, and PER1 and PER3 genes may indicate individual circadian rhythms.
6 citations,
December 2011 in “Nature” The circadian clock in skin cells controls their growth and rest cycles.
38 citations,
April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
13 citations,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
55 citations,
March 2010 in “Aging” Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.
47 citations,
May 2012 in “Wiley Interdisciplinary Reviews-Developmental Biology” The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
161 citations,
August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Platelet-rich Plasma Gel may help treat en coup de sabre scleroderma, improving symptoms and skin quality with minimal side effects.
5 citations,
December 2016 in “International journal of biometeorology” Bright light during the day doesn't change most human clock genes but may slightly increase Rev-erb-ß.
66 citations,
June 2010 in “Experimental Dermatology” The hair follicle is a great model for research to improve hair growth treatments.
42 citations,
March 2018 in “PLOS Biology” Autophagy is important for human hair growth and health.
31 citations,
July 2017 in “Clinical Science” MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
15 citations,
November 2015 in “Trends in biotechnology” Gene regulation could revolutionize hair color by altering pigmentation from within.
212 citations,
September 2015 in “Journal of Investigative Dermatology” The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
185 citations,
February 2018 in “Journal of Investigative Dermatology” Melatonin may benefit skin health and could be a promising treatment in dermatology.
166 citations,
August 2010 in “Proceedings of the National Academy of Sciences of the United States of America” Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.
113 citations,
March 2018 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.
98 citations,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
82 citations,
September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
77 citations,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
63 citations,
March 2016 in “International Journal of Molecular Sciences” Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.
61 citations,
June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” Light can turn on hair growth cells through a nerve path starting in the eyes.
59 citations,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
49 citations,
April 2016 in “International journal of molecular sciences” Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.
42 citations,
February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.