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Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

One minoxidil-sensitive potassium channel exists in human hair follicles.

Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.