Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the role of natural killer cells in the pathogenesis of blistering diseases and proposes further research on their interaction with the skin, reporting no new clinical results.

This study highlights that patients with pemphigus experiencing cutaneous involvement endure pruritus levels approaching those of bullous pemphigoid, impacting their quality of life alongside other autoimmune blistering diseases.

This study found that more than 70% of patients with autoimmune blistering diseases experienced alopecia, with about 10% having scarring alopecia, and elevated Dsg1 ratios were linked to hair loss in pemphigus vulgaris.

This study observed that people with autoimmune blistering skin disorders report higher food intolerance rates, particularly avoiding alcohol, citrus, and spicy foods, and suggests potential dietary influences on symptom management.

This case report describes how a treatment with mycophenolate mofetil and prednisone may be effective in managing autoimmune subepidermal blistering dermatosis in dogs while allowing for steroid reduction.

This review explores the role of Granzyme B in autoimmune skin diseases and highlights its potential as a therapeutic target due to its involvement in impaired barrier function and inflammation.

This review discusses the link between Parkinson's disease and dermatological disorders, highlighting that skin biomarkers may aid in the diagnosis of Parkinson's, but it reports no new clinical results.

This case report in a child suggests that lichen planus pemphigoides may represent a heterogeneous group of disorders, potentially triggered by conditions like varicella.

This article reviews the recognition and management of Staphylococcus aureus toxin-mediated diseases, but it does not present new research findings.

This study observed that pruritus and xerosis were the most common skin complaints among the geriatric population attending a dermatology clinic in Puducherry.

This chapter reviews various fungal skin diseases affecting cattle but does not report new research findings; it focuses on rare, inherited, and congenital conditions like follicular dysplasia and cutaneous asthenia.

Cocaine use can cause a blistering skin disease.

This study found that desmocollin 1 is crucial for strong adhesion and barrier maintenance in the mouse epidermis, with its absence leading to skin and hair issues resembling chronic dermatitis.

This review discusses three newly identified forms of epidermolysis bullosa related to mutations in DST-e, EXPH5, and ITGA3, offering insights into their genetic and clinical characteristics but reports no new clinical results.

This review discusses the range of cutaneous immune-related adverse events induced by immune checkpoint inhibitors and the proposed mechanisms underlying these skin reactions, but reports no new clinical results.

This study found that in skin blister healing, hair follicle development is compromised as stem cells repair wounds at the expense of morphogenesis gene expression.

In this review designed for continuing education, the authors highlight the importance for clinicians to differentiate facial disorders clinically, as some can be life-threatening, and critically assess laboratory methods for diagnosing pemphigus diseases.

This study developed a pemphigus model in mice showing that anti-Desmocollin 3 and anti-Desmoglein 3 antibodies lead to more severe disease, suggesting diverse antigens contribute to varying human pemphigus phenotypes.

In this study, researchers developed a pemphigus mouse model expressing anti-Desmocollin 3 antibodies and found it mimicked atypical pemphigus with distinct pathological features compared to the standard Desmoglein 3 model.

This study found that alopecia areata patients have higher odds of certain comorbidities like ulcerative colitis and vitiligo, while showing lower odds for conditions like hypertension and type 2 diabetes compared to healthy controls.

This review discusses changes in keratin structure or gene expression that result in various skin disorders and reports no new clinical findings.

In this study of elderly patients at an Indian medical center, researchers found that xerosis was the most common physiological skin change and pruritus was the most frequent complaint.

New findings on hair keratin, wound healing, and skin blistering were presented.

In this study, researchers found that in growing skin tissue, epidermal wound healing occurs at the expense of normal skin development, as it impairs hair follicle growth and does not activate tissue morphogenesis genes.

This review discusses recent findings on the mechanisms driving bullous pemphigoid, highlighting epitope spreading and the roles of regulatory T cells, and reports no new experimental results.

This study described a rare case of bullous pemphigoid presenting as cicatricial alopecia in a Hispanic female, successfully treated with a combination of oral methotrexate and topical steroids.

This study reported that specific inhibition of the classical complement pathway with BIVV009 prevented C3 deposition along the dermal-epidermal junction in bullous pemphigoid, reflecting its potential efficacy.

Loss of Dsc3 function in the epidermis impaired cell adhesion, leading to blistering and hair loss, which suggests a potential cause of PV-like skin diseases according to this study.

This review discusses the role of mechanical forces in skin homeostasis and disease development, including their impact on conditions like keloids, androgenetic alopecia, and acral melanoma, and reports no clinical results; the authors propose modifying these forces as a potential therapeutic strategy.

This study developed a 3D bioprinted skin model to mimic pemphigus vulgaris, providing a tool to study disease mechanisms and test targeted therapies by reproducing the architecture and pathogenic disruptions of native skin.