1 citations
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November 2025 in “Science Advances” This research identified two genetic variants that influence the white-spotted coat patterns in Holstein-Friesian cattle, involving regulatory changes in the MITF and KIT genes, confirmed through mouse models, along with possible effects on coat patterns in other cattle breeds.
158 citations
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May 2003 in “Journal of Investigative Dermatology” This study observed that hair follicle mesenchyme in mice exhibits significant plasticity during the hair cycle, with cell migration and changes in papilla size impacting hair production.
340 citations
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September 2014 in “PLOS Genetics” This study found that while genetic ancestry affects physical appearance traits in Latin American populations, it accounts for only a modest portion of the observed variation.
196 citations
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March 2016 in “Nature Communications” In this study, researchers identified 18 genetic associations with scalp and facial hair traits in Latin Americans, including novel loci for hair greying and balding, with implications for understanding hair evolution.
90 citations
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February 2013 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with polycystic ovary syndrome have higher global adiposity and increased visceral fat, particularly in the ip and mesenteric depots, compared to women without androgen excess.
70 citations
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February 2012 in “Human Reproduction” This study found a high prevalence of clinical signs and functional disorders of androgen excess in premenopausal women, with idiopathic hyperandrogenism and idiopathic hirsutism rates similar to PCOS.
23 citations
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January 2009 in “Veterinary Dermatology” This study found that recombinant hepatitis B vaccine may increase the risk of alopecia areata onset in older predisposed mice but larger trials suggest this effect might lie within normal variation.
7 citations
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January 2022 in “Animal Reproduction” This review examines rodent models to explore how maternal conditions like undernutrition, obesity, hypoxia, and androgen exposure affect fetal programming and metabolic outcomes in offspring, but presents no new clinical findings.
49 citations
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November 2013 in “JAMA dermatology” This study found that topical clobetasol propionate cream was more effective than hydrocortisone cream in reducing hair loss surface area in children with patchy alopecia areata over 24 weeks, with no serious adverse effects.
3 citations
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November 2024 in “Cancers” This meta-analysis involving over 3.7 million patients found that diabetes mellitus is associated with a reduced risk of developing prostate cancer, although significant heterogeneity exists among studies; however, a family history of prostate cancer was linked to a higher risk.
August 2024 in “Cosmetics” This review highlights caffeine's diverse benefits in cosmetics and nutricosmetics, noting its antioxidant properties, ability to treat skin disorders like androgenic alopecia, and potential to enhance sunscreen effectiveness, though penetration into deeper skin layers remains challenging.
35 citations
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May 2020 in “Frontiers in Pharmacology” This review provides a comprehensive overview of the mechanisms, efficacy, and adverse reactions of drugs commonly used for treating benign prostatic hyperplasia but reports no new clinical results.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that infiltrating M2 macrophages promote wound-induced hair neogenesis in mice by producing growth factors that activate the wnt signaling pathway during the late phase of wound healing.
50 citations
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December 2009 in “Journal of The European Academy of Dermatology and Venereology” This study found that latanoprost may be effective for treating eyelash alopecia areata, achieving cosmetically acceptable regrowth in 45% of patients.
40 citations
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January 2013 in “International journal of trichology” This study found that among women with frontal fibrosing alopecia, 100% showed dermoscopic elements suggestive of the condition, with perifollicular erythema often indicating disease activity.
72 citations
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January 2001 in “Drugs” This review discusses current and emerging drug therapies for treating androgenetic alopecia and alopecia areata, and reports no clinical results; it highlights a need for improved and novel treatments.
4 citations
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June 2020 in “BMC Ophthalmology” This case report suggests that prolonged use of topical minoxidil for androgenic alopecia may cause central serous chorioretinopathy, and oral eplerenone appeared effective in resolving symptoms in the patient presented.
4 citations
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April 2016 in “Journal of The American Academy of Dermatology” Microneedling with platelet-rich plasma can improve different types of hair loss.
3 citations
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May 2010 in “Victorian literature and culture” This article discusses the substantial presence of advertising material in the original serial numbers of "The Pickwick Papers," accounting for almost one third of the content, but presents no new results.
January 2020 in “Asian journal of applied science and technology” This source provides an overview of the dietary recommendations for macronutrient intake and the benefits of plant-based diets, including meeting essential amino acid needs through combining plant proteins and the advantages of consuming complex carbohydrates and adequate fiber for health.
April 2016 in “Journal of The American Academy of Dermatology” The study found that Temporal Triangular Alopecia often starts in early childhood, mainly affects the left side of the scalp, and has no effective treatment except surgery.
April 2016 in “Journal of The American Academy of Dermatology” The study found that Temporal Triangular Alopecia often starts in early childhood, while Folliculitis Decalvans is characterized by tufted hairs and redness around hair follicles.
March 2014 in “Journal of The American Academy of Dermatology” The document lists various dermatology topics, treatments, and diagnostic methods.
November 2012 in “Actas Dermo-Sifiliográficas” An 86-year-old man had a rare tongue melanoma but refused treatment, showing the need for early cancer detection and treatment.
53 citations
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May 1990 in “Journal of Dermatology” In this animal study, topical minoxidil shortened the telogen phase of hair growth cycles in rats, suggesting it may stimulate certain follicles to progress more rapidly to anagen.
34 citations
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December 1995 in “Pediatric Dermatology” In this study, researchers reported a 0.11% occurrence of congenital triangular alopecia, recommending surgical treatment for women but not for men due to later potential development of androgenic alopecia.
16 citations
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January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This review discusses frontal fibrosing alopecia and reports no clinical results; the authors note that no therapeutic options tested, including corticosteroids, finasteride, and minoxidil, have shown clear benefits.
3 citations
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November 1999 in “Journal of Cutaneous Medicine and Surgery” AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.
May 2023 in “Research Square (Research Square)” This study found that the natural product Shi-Bi-Man significantly promoted hair regeneration in cynomolgus monkeys, increasing hair follicle number and activation by boosting specific protein markers and interactions in Laminin-related pathways.
194 citations
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March 2003 in “American Journal of Pathology” This study found that psychoemotional stress disrupts hair growth in mice by terminating anagen and suggests a potential pathway for pharmacological management of stress-related hair loss in humans.