research A Glutathione-Dependent Control of the Indole Butyric Acid Pathway Supports Arabidopsis Root System Adaptation to Phosphate Deprivation
Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.
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research Decreased Alcohol Consumption Among Former Male Users of Finasteride with Persistent Sexual Side Effects: A Preliminary Report
Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.
research Interaction Between Stem Cell Factor and Endothelin-1: Effects on Melanogenesis in Human Skin Xenografts
SCF and ET-1 together significantly increase skin pigmentation and melanin production.
research Current Perspectives on the Physiological Activities of Fermented Soybean-Derived Cheonggukjang
Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.
research An Integrated Analysis of Cashmere Fineness lncRNAs in Cashmere Goats
lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.
research Regenerative Medicine Meets Mathematical Modelling: Developing Symbiotic Relationships
Mathematical modeling can improve regenerative medicine by predicting biological processes and optimizing therapy development.
research Intralesional Therapy for the Treatment of Keratoacanthoma
Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.
research Allopregnanolone Mediates the Exacerbation of Tourette-Like Responses by Acute Stress in Mouse Models
Stress worsens Tourette symptoms by increasing allopregnanolone levels.
research Stem Cells and Aberrant Signaling of Molecular Systems in Skin Aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
research Guidelines for the Use of Acitretin in Psoriasis
Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.
research Efficacy of Combination Therapy of Inositols, Antioxidants, and Vitamins in Obese and Non-Obese Women with Polycystic Ovary Syndrome: An Observational Study
The combination therapy improved PCOS symptoms in both obese and non-obese women, with weight loss in the obese group.
research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and SCD1 and SOAT1 Activity
Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
research The Therapeutic Potential of CRTH2/DP2 Beyond Allergy and Asthma
CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.
research Expression of AKT1 Along with AKT2 in Granulosa-Lutein Cells of Hyperandrogenic PCOS Patients
The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
research Platycladus Orientalis Leaves: A Systematic Review on Botany, Phytochemistry, and Pharmacology
The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.
research Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men
Finasteride can cause sexual problems and depression in young men.
research Human Gene Correlation Analysis: A Tool for the Identification of Transcriptionally Co-Expressed Genes
The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.
research Metabolic and Pathologic Profiles of Human LSS Deficiency Recapitulated in Mice
Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.
research Effect of Bioclimatic Area and Season on Phenolics and Antioxidant Activities of Rosemary (Rosmarinus Officinalis L.) Leaves
Rosemary's antioxidant content changes with the climate and season.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research The Metabolic Syndrome-Associated Small G Protein ARL15 Plays a Role in Adipocyte Differentiation and Adiponectin Secretion
ARL15 is important for fat cell development and the release of the hormone adiponectin.
research Pharmacological Activation of Estrogen Receptors-α and -β Differentially Modulates Keratinocyte Differentiation with Functional Impact on Wound Healing
Activating ER-β, not ER-α, improves skin cell growth and wound healing.
research Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the Ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine
Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
research Cicatricial Alopecia Research Foundation Meeting, May 2016: Progress Towards the Diagnosis, Treatment, and Cure of Primary Cicatricial Alopecias
The meeting focused on understanding, diagnosing, and finding treatments for irreversible hair loss diseases.
research Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia
Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Minoxidil Prevents MDMA-Induced Serotonin Depletions: Role of Mitochondrial ATP-Sensitive Potassium Channels, Akt, and ERK
Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.
research Roles of Steroid Sulfatase in Brain and Other Tissues
Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
research Signaling and Gene Expression for Water-Tolerant Legume Nodulation
The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.
research Alopecia: Unapproved Treatments or Indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.