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Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Omics techniques are needed to understand the scalp microbiome's role in alopecia areata for new treatments.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Mannosylerythritol lipids are good for skin and hair care products.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Certain fungi and bacteria help orchid seeds germinate and plants grow better.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Certain drugs that block specific enzymes can help treat prostate diseases.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.