research PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
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research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–Like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Transcriptomic Analysis Reveals Critical Genes for the Hair Follicle of Inner Mongolia Cashmere Goat from Catagen to Telogen
Key genes regulate hair follicle phase changes in Inner Mongolia cashmere goats.
research Medicinal Plants with Traditional Use: Ethnobotany in the Indian Subcontinent
Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.
research A Randomized, Double-Blind, Vehicle-Controlled Clinical Study of Hair Regeneration Using Adipose-Derived Stem Cell Constituent Extract in Androgenetic Alopecia
ADSC-CE treatment safely increases hair density and thickness in androgenetic alopecia patients.
research Systematic Review of Platelet-Rich Plasma in Treating Alopecia: Focusing on Efficacy, Safety, and Therapeutic Durability
Platelet-rich plasma (PRP) is a safe and potentially effective way to treat hair loss, especially when combined with minoxidil.
research Hyaluronic Acid-Based Hydrogels for Full-Thickness Wound Repairing and Skin Regeneration
Hyaluronic acid-based HA2 hydrogel helps heal skin wounds better with less scarring.
research An Updated Review on Hibiscus Rosa-Sinensis Phytochemistry and Medicinal Uses
Hibiscus rosa-sinensis may help treat various health issues and promote hair growth, but more research is needed for safety.
research A Missing Piece: The Spiny Mouse And The Puzzle Of Menstruating Species
The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
research Skin-Derived Stem Cells as a Source of Primordial Germ Cell and Oocyte-Like Cells
Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
research Human Gene Correlation Analysis: A Tool for the Identification of Transcriptionally Co-Expressed Genes
The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.
research Pharmacological Activation of Estrogen Receptors-α and -β Differentially Modulates Keratinocyte Differentiation with Functional Impact on Wound Healing
Activating ER-β, not ER-α, improves skin cell growth and wound healing.
research Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing
KLF4 is important for maintaining skin stem cells and helps heal wounds.
research Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia
Nanotechnology improves minoxidil treatment for hair loss.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Adipose Stem Cells From Type 2 Diabetic Mice Exhibit Therapeutic Potential In Wound Healing
Fat stem cells from diabetic mice can still help heal wounds.
research A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia
Using micro-needling, low-level laser therapy, and platelet-rich plasma together significantly improves hair growth in people with hair loss.
research Alginate-Based Hydrogel Containing Minoxidil/Hydroxypropyl-β-Cyclodextrin Inclusion Complex for Topical Alopecia Treatment
A new gel containing minoxidil can treat hair loss effectively, potentially reducing side effects and improving treatment.
research COVID-19 and Andrology: Recommendations of the French-Speaking Society of Andrology
Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.
research New Ethanol and Propylene Glycol Free Gel Formulations Containing a Minoxidil-Methyl-Beta-Cyclodextrin Complex as Promising Tools for Alopecia Treatment
New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.
research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research Phenolsulphotransferase: Localization in Kidney During Human Embryonic and Fetal Development
The enzyme PST is found in developing human kidneys and helps with detoxification and development.
research The Probable Destructive Mechanisms Behind COVID-19 on Male Reproductive System and Fertility
COVID-19 may harm male fertility and damage the reproductive system.
research AIRMESS – Academy of International Regenerative Medicine & Surgery Societies: Recommendations in the Use of Platelet-Rich Plasma (PRP) and Autologous Stem Cell-Based Therapy (ASC-BT) in Androgenetic Alopecia and Wound Healing
Use PRP and ASC-BT for hair loss and wound healing, but more research needed.
research Can Dermal Delivery of Therapeutics Be Improved Using Thermoresponsive Nanogels?
Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.
research The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
research Increased Frequency of the DI Genotype of the Angiotensin-I Converting Enzyme and Association of the II Genotype with Insulin Resistance in Polycystic Ovary Syndrome
The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.
research Therapeutic Options in Polycystic Ovary Syndrome
The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.
research MoS2 Nanoclusters-Based Biomaterials for Disease-Impaired Wound Therapy
The SA-MS hydrogel is a promising material for improving wound healing and skin regeneration in diseases like diabetes and skin cancer.