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This review discusses the therapeutic potential of Ganoderma lucidum's secondary metabolites, noting their diverse health benefits, such as anticancer and antioxidant effects, without presenting new experimental results.

This study found that certain bioactive mushroom metabolites may inhibit the enzyme SRD5A2 more effectively than finasteride in computational models, suggesting potential for further research in treating androgenic alopecia.

This study suggests that three mushroom-derived bioactive compounds, Zhankuic acid A, Sterenin M, and Melleolide K, may effectively inhibit SRD5A2 and stabilize its interaction, indicating potential for treating androgenic alopecia.

This study found that certain metabolites from the plants Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana may support hair follicle growth by promoting dermal papilla cell proliferation, supporting their traditional use in hair care.

This study found that Murraya koenigii extracts and compounds demonstrated potent antibacterial and cytotoxic activities, with notable effects against antibiotic-resistant strains and cancer cell lines, supporting its potential for further pharmacological investigation.

This systematic review highlights the diverse uses and bioactivities of Impatiens plants, particularly their antimicrobial, cytotoxic, anti-inflammatory, anti-anaphylactic, and antioxidant properties, while noting the need for more research to validate their ethnobotanical applications and isolate major bioactive compounds.

This review highlights the potential of plant-derived natural compounds as biocompatible and biodegradable materials in dermal and transdermal delivery systems, emphasizing their unexplored benefits and detailing recent advances in isolation techniques and drug delivery technologies.

This study identified that the enzyme CYP2B12 is skin-specific and likely plays a role in the metabolism of arachidonic acid, a key component in lipid signaling within sebaceous glands.

This study found that aeroponic cultivation significantly increased the growth and bioactive compound content of Cannabis Sativa roots compared to soil cultivation.

This study found that while nicotinic acid significantly inhibited human sebaceous organoid growth in vitro, the predicted skin concentrations from gut microbiome-derived levels were far below the effective dose, suggesting high oral doses would be necessary for therapeutic effects.

In this randomized double-blind study, 160 adults with alopecia areata showed significant improvements in hair loss severity after using a bioactive peptide cosmetic product that mimics platelet-rich plasma, while the placebo group showed no significant change, underlining the treatment's potential effectiveness.

In this study, SCOBY kombucha gel significantly accelerated incision wound healing in mice, particularly with a 12% concentration, as shown by a notable reduction in wound size compared to lower concentrations and controls.

This review examines the pharmacological evidence and bioactive compounds in Hibiscus plants, supporting their potential importance for developing treatments for chronic and degenerative diseases, though more research is needed.

This study analyzed the bioactive compound profiles of Allium longisepalum from Iran, finding unique metabolites with potential antioxidant, allelopathic, antibacterial, anti-inflammatory, anticarcinogenic, and hair growth-enhancing properties, revealing the plant's chemical diversity and therapeutic potential.

This review found that secondary metabolites from herbal plants, including flavonoids and alkaloids, show potential in promoting hair growth through mechanisms like anagen phase prolongation and enzyme inhibition, but more clinical trials are needed to confirm their efficacy.

In this review, several studies on Astragalus species, particularly Astragalus membranaceus, highlight their skin rejuvenating, photoprotective, antimicrobial, and wound-healing properties, though the authors note limitations due to reliance on non-human studies and short trial durations.

This review highlights the potential of marine macroalgae as a largely untapped resource for developing new active ingredients in the cosmetic industry, emphasizing their role in supporting circular economy models by utilizing waste from other industrial sectors.

In this study, researchers isolated and identified diverse endophytes from plants in Asia, finding that these microorganisms have significant potential for producing useful metabolites, including enzymes and antibiotics.

This review analyzed current studies on metabolite production from the medicinal fungus Cordyceps militaris, focusing on its fermentation modes and biological functions, and emphasizes the need for modern fermentation processes to enhance industrial production.

This review critically examines scientific evidence on the health benefits of rosemary bioactives, finding potential in managing age-related diseases and skin aging conditions, and discusses their application in functional foods and aromatherapy, along with associated safety concerns.

This study found that girls with prepubertal simple hypertrichosis had significantly higher plasma levels of dihydrotestosterone compared to controls, which does not align with other androgen markers and warrants further investigation.

This study found that microwave-assisted extraction significantly increased the yield of secondary metabolites, including phenolic and flavonoid content, from Nardostachys jatamansi, enhancing its anti-Alzheimer's potential compared to conventional extraction methods.

This study found that Lactobacillus acidophilus cell-free supernatant caused significant cytotoxicity, reduced migratory ability, and induced apoptosis in cervical cancer cell lines, suggesting its potential as a non-toxic adjunct therapy for cervical cancer.

This study observed that rhizobacterial strain RT3 significantly improved drought tolerance in lettuce by increasing survival rates and fresh biomass after rewatering, with metabolites such as proline and glycine enhancing stress resilience.

This study found that while rat models treated with letrozole and dihydrotestosterone exhibit altered sterol, leukotriene, and steroid hormone profiles similar to human PCOS, significant differences remain.

This review highlights the pharmaceutical potential of secondary metabolites from Juniperus species, noting promising antitumor, antibacterial, and antiviral activities, but reports no new experimental findings.

This study analyzed Sphenodesme involucrata var. paniculata leaves and found high carbohydrate and calcium content, along with several bioactive compounds, supporting their use in traditional medicine for their nutrient-rich properties.

This study found that olive and olive oil may significantly reduce cardiovascular disease risk, cholesterol, and blood pressure, while offering antioxidant protection through bioactive metabolites like oleuropein.

This review highlights the bioactive compounds in the brown seaweeds Undaria pinnatifida (wakame) and Saccharina japonica (kombu), detailing their various health benefits based on clinical studies, notably from Japan and elsewhere.

This study identified the main secondary metabolites in Ziziphus jujuba seeds and confirmed that UPLC-MS/MS and GC-MS effectively demonstrate their pharmaceutical quality.