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This study used molecular docking simulations to identify approved drugs, including Bedaquiline and Telmisartan, with potential to treat Onchocerca volvulus infections by inhibiting key protein targets, suggesting these drugs could be repurposed for onchocerciasis treatment with further validation.

In a conditional knockout mouse model, this study found that loss of the transcription elongation factor SPT6 in basal keratinocytes led to psoriasis-like skin inflammation and delayed wound healing, suggesting SPT6 plays a crucial role in maintaining epidermal immune quiescence by suppressing proinflammatory NF-κB signaling.

This study identified three Ayurvedic compounds that may serve as potential treatments against the macrolide-resistant enzyme murE of *Tropheryma whipplei*, addressing challenges in treating Whipple disease.

In this study, combining stromal cells and PRP resulted in a significantly higher cell count and volume than using a saline group, suggesting increased potential efficiency; however, clinical outcomes need further evaluation.

This study found that a keratin film made from human hair supports enhanced cell proliferation and viability compared to collagen I, suggesting potential for cell culture applications.

In this study, researchers identified ten key genes involved in the periodic development of hair follicles in cashmere goats, highlighting the importance of the Wnt signaling pathway and cell cycle in this process.

This study identified key molecular differences between Long and Short hair type cashmere goats, suggesting hair type differentiation is linked to structural assembly and follicle remodeling.

This review suggests that curcumin and piperine may offer a promising multi-target therapeutic approach for alopecia by simultaneously modulating androgenic and inflammatory pathways, though experimental and clinical validation are necessary to confirm their efficacy.

In this review, researchers explored the potential of a curcumin–piperine combination in alopecia management through computational analyses, highlighting its capacity to modulate multiple pathways involved in hair follicle homeostasis, although further experimental and clinical validation is necessary to confirm its efficacy.

This study found that modifying biphasic calcium phosphate/poly(methyl methacrylate) bone cement with human hair keratin improves its hydrophilicity, mechanical properties, and supports bone repair in rats, indicating potential for orthopedic applications.

This review explores the potential of alginate as a promising alternative to donor tissue for corneal transplantation due to its adaptability, transparency, and low immunogenicity, and discusses how chemical modifications can enhance its properties for use in corneal tissue engineering.

This review discusses the applications of biopolymeric composites in controlled drug release, tissue engineering, and wound healing, but reports no new experimental results, highlighting the need for further development and analysis.

This study discusses a hypothesis for repurposing non-cancer drugs and combining micronutrients to target cancer and cancer stem cells with fewer side effects, suggesting a potential new approach for more effective cancer therapy.

This study suggests that Cepharanthine, a monomer in traditional Chinese medicine, may help treat COVID-19 by affecting multiple signaling pathways, and that TNF and IL-17 inhibitors used in rheumatoid arthritis, ankylosing spondylitis, and gouty arthritis might also be beneficial.

This review highlights challenges in developing drugs targeting the Wnt/β-Catenin signaling pathway for cancer due to its complexity and essential roles in normal tissue. It explores targeted protein degradation technology as a promising strategy to overcome these challenges, suggesting potential new avenues for drug development.

In this study, researchers developed a programmable system using engineered nanovesicles from hair follicle stem cells to modulate immune responses, which showed promise in precisely controlling inflammation, promoting immune balance, and accelerating wound healing, particularly for infected wounds.

This study created a detailed atlas of endogenous peptides across 13 maize tissues during various developmental phases, revealing a complex regulatory network where peptide abundance doesn't always align with their source proteins, signaling unique roles in maize development.

In this study using a virtual screening approach, eriocitrin and silymarin were identified as potent flavonoid compounds that strongly and stably interacted with 5α-reductase type II, suggesting potential development as novel treatments for androgenic alopecia.

This study suggests that age-related changes in skin elasticity reduce its stability against wrinkling, and anti-aging strategies should focus on addressing elastic mismatches between skin layers.

This study found that the mechanical stiffening of the human hair follicle along the first millimeter is linked to changes in the keratin network architecture and composition during keratinization.

This study observed that biodegradable PVA/agar films with incorporated Achillea millefolium L. essential oil, especially at 1% (v/v), demonstrated good mechanical performance and selective antibacterial activity against E. coli, suggesting their potential as wound dressings.

In this study, a mechanical model was developed to describe and validate the effectiveness of overnight hair curling, suggesting that combining it with hair fixatives can maintain a desired curl for over a day.

In this study, the authors found that applying hypobaric pressure to the skin significantly increases the transdermal permeation of large molecules by enhancing diffusion, despite the associated skin stretching and hair follicle enlargement not fully explaining this effect.

This study found that a newly developed supramolecular FPC hydrogel effectively promotes wound healing through its anti-inflammatory and angiogenic properties, making it a promising material for wilderness first aid due to its storage convenience, sprayability, and ability to speed up wound recovery.

In this study, peptide nanofiber gels RG and RJ significantly accelerated the healing of deep second-degree burn wounds in vivo, with greater wound closure rates and enhanced tissue regeneration compared to controls, attributed to increased angiogenesis and reduced systemic inflammation.

This article reviews the generation of complex integument patterns through genetic, chemical, and environmental influences, with applications in tissue engineering, but reports no new experimental results.

This study reveals that β-catenin and retinoic acid are key regulators in the gene networks controlling the fate of skin appendages, such as scales and feathers.

This study identified a new cis-regulatory element in the mouse Hr gene that influences its expression in skin and brain cells, highlighting a complex molecular network involved in hair follicle formation.

This study found that the moisture content of human hair significantly influences the type of fracture under tensile loading, with low or high humidity levels leading to smooth fractures and intermediate humidity resulting in step fractures.

This study observed that repeated perm treatments decrease disulfide bonds in hair due to their conversion largely into cysteic acid, affecting the waving efficiency depending on the reduction agent used.