Exploring the Role of Two Polypeptide Nanofiber Gels Derived from RADA16-I Self-Assembly in Accelerating Burn Wound Healing

    July 2025 in “ Scientific Reports ”
    Chaokun Song, Sijia Li, Chenyang Zhang … Weiqiang Chen
    Studysummary In this study, peptide nanofiber gels RG and RJ significantly accelerated the healing of deep second-degree burn wounds in vivo, with greater wound closure rates and enhanced tissue regeneration compared to controls, attributed to increased angiogenesis and reduced systemic inflammation.
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    Research cited in this study 5

    1. Release Systems Based on Self-Assembling RADA16-I Hydrogels With a Signal Sequence Which Improves Wound Healing Processes Scientific Reports · 2023
    2. Combination of an Engineered Lactococcus Lactis Expressing CXCL12 with Light-Emitting Diode Yellow Light as a Treatment for Scalded Skin in Mice Microbial biotechnology · 2021
    3. Adipose Mesenchymal Stem Cells Combined with Platelet-Rich Plasma Accelerate Diabetic Wound Healing by Modulating the Notch Pathway Stem Cell Research & Therapy · 2021
    4. Injectable Polypeptide-Protein Hydrogels for Promoting Infected Wound Healing Advanced Functional Materials · 2020
    5. Wound Healing: A Cellular Perspective Physiological Reviews · 2018