15 citations
,
April 2020 in “Journal of The American Academy of Dermatology” In this study, intradermal injection of botulinum toxin was associated with increased hair growth in men with androgenetic alopecia through the suppression of TGF-β1 secretion from dermal papilla cells.
13 citations
,
April 2015 in “Journal of Dermatology” In this study, long-term finasteride treatment improved androgenetic alopecia in Japanese men, with younger age and less advanced disease at treatment start predicting better efficacy.
4 citations
,
April 2020 in “Journal of Cosmetic Dermatology” This study found that men with early androgenetic alopecia have a higher prevalence of hyperuricemia compared to those without the condition.
2 citations
,
April 2018 in “Journal of Cosmetic Dermatology” This study found that hair shaft exit angles in patients undergoing strip hair restoration increased after the tumescence injection and further increased after strip excision.
1 citations
,
July 2018 in “Elsevier eBooks” This review covers androgenetic alopecia's epidemiology, pathogenesis, current management options, and research trends, concluding that no definitive cure exists despite extensive interest and ongoing genetic research efforts.
March 2019 in “International Journal of Dermatology” This study observed that different types of hairline recession increased the perceived facial age of East Asian males, with hair loss type C2 or U2 making those in their 30s appear significantly older.
May 2020 in “Journal of Asian Medical Students' Association” This study concluded that psychological well-being and self-image among Filipino males with androgenetic alopecia may be influenced by age, education level, and disease severity.
151 citations
,
August 2010 in “British Journal of Dermatology” This guideline reviews the diagnosis of androgenetic alopecia and offers expert consensus recommendations tailored to males, females, and adolescents, but reports no new clinical results.
105 citations
,
January 2009 in “Medicine” This study found that ethinylestradiol and high-dose cyproterone acetate significantly reduced hirsutism scores and were effective for treating acne and alopecia in women with hyperandrogenism.
101 citations
,
January 2012 in “Annals of Dermatology” In this study, researchers found that androgenetic alopecia significantly harms quality of life, particularly in younger patients, those with more severe or long-term alopecia, and those who have sought non-medical hair care.
100 citations
,
April 2010 in “Expert Opinion on Pharmacotherapy” This article reviews existing treatments for male-pattern hair loss, noting that while they can slow progression, they generally achieve only partial hair regrowth.
91 citations
,
August 2015 in “Anais Brasileiros De Dermatologia” This review discusses the clinical, epidemiological, and pathophysiological aspects of female pattern hair loss, reporting no new research findings.
88 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article reviews recent advancements in understanding and treating androgenetic alopecia, focusing on new genetic insights, stem cell roles, and diagnostic tools, without reporting new clinical results.
67 citations
,
April 2018 in “JAMA Dermatology” This study found that endocrine therapy for breast cancer is associated with a pattern of hair loss similar to androgenetic alopecia, negatively impacting quality of life despite mild severity.
52 citations
,
June 2009 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses the pathogenesis and treatment of androgenetic alopecia, highlighting genome associations and newer topical formulations, but reports no new clinical results.
41 citations
,
October 2011 in “Journal of Dermatology” This study observed that long-term use of finasteride in Japanese men with androgenetic alopecia was associated with progressive hair regrowth in 87.1% of participants without significant safety concerns.
38 citations
,
March 2017 in “Expert Opinion on Investigational Drugs” This review examines the potential of bimatoprost for treating various types of eyelash and eyebrow hypotrichosis, discussing its pharmacological properties but providing no new clinical results.
36 citations
,
June 2018 in “Journal of Dermatology” This article updates Japanese guidelines for diagnosing and treating male and female-pattern hair loss, recommending specific drugs and therapies while advising against certain treatments for female-pattern hair loss.
35 citations
,
January 2014 in “Postepy Dermatologii I Alergologii” This study found that increased dihydrotestosterone levels were observed in both androgenetic alopecia patients and controls, suggesting that follicle sensitivity to DHT may be more critical than DHT levels for alopecia development.
28 citations
,
November 2020 in “Journal of Controlled Release” In this study, microneedles combined with finasteride nanostructured lipid carriers (FIN-NLC-MNs) were found to enhance skin penetration and specifically target hair follicles, promoting hair growth and gene regulation in androgenetic alopecia.
26 citations
,
December 2015 in “Journal of The European Academy of Dermatology and Venereology” This article introduces a new grading system called the FPHL Severity Index to better identify and monitor early stages of female pattern hair loss using clinical criteria.
21 citations
,
January 2012 in “Annals of Dermatology” This study reported that Ell-Cranell® alpha 0.025% solution significantly increased hair counts and diameter in Korean women with female pattern hair loss over an 8-month period, showing both efficacy and safety.
20 citations
,
January 2018 in “Expert Opinion on Drug Safety” This review discusses androgenetic alopecia management with 5α-reductase inhibitors, emphasizing that while dutasteride shows superior efficacy, finasteride is suggested as preferable due to predictable adverse effects and preservation of physiological roles.
20 citations
,
December 2013 in “Clinical and Experimental Dermatology” This study found that among Korean men with AGA, drinking and smoking were associated with greater hair loss severity, while family history was linked to more severe hair loss and earlier onset.
18 citations
,
January 2013 in “Annals of Dermatology” This study suggests the average age of onset for androgenic alopecia may be decreasing, but a longer-term study is needed to confirm this observation.
16 citations
,
September 2018 in “Journal of Ethnopharmacology” This review discusses the role of inheritance, androgens, and microinflammation in androgenetic alopecia and suggests some plant-based folk remedies may help address these factors but reports no new clinical results.
15 citations
,
January 2018 in “Annals of Dermatology” Wigs significantly improve the well-being of people with severe hair loss.
15 citations
,
January 2017 in “JAMA Dermatology” This study found that topical minoxidil improved female pattern hair loss, finasteride was not more effective than placebo, and laser devices showed inconsistent results but increased hair count compared to baseline.
15 citations
,
January 2013 in “Journal of Cutaneous and Aesthetic Surgery” This study observed that direct hair transplantation, as a modification of follicular unit extraction, was effective in improving baldness in the majority of treated male patients.
13 citations
,
March 2019 in “Journal of Dermatological Treatment” This review explores the inconsistent therapeutic effects and side effects of finasteride for androgenic alopecia, highlighting the need for further research to better predict individual patient responses.