126 citations
,
January 2009 in “International Journal of Trichology” This review discusses the potential role of oxidative stress in hair graying and age-related alopecia, emphasizing the need for new strategies to counteract these effects, but reports no new results.
26 citations
,
September 2002 in “Dermatologic Surgery” This study reports that the prevalence of male pattern baldness in Asians is higher than previously believed, with potential links to socioeconomic factors and westernized diets, though the exact cause remains unclear.
13 citations
,
June 2007 in “Journal of Dermatological Science” This study identified several genes regulated by dihydrotestosterone in an SV40T-transformed human dermal papilla cell line, which may play a role in androgen-mediated hair growth regulation.
57 citations
,
January 2004 in “Journal of Endocrinology” This study found no support for the idea that male-pattern baldness in female-to-male transsexuals indicates an increased risk of coronary heart disease through androgenic effects on classic risk factors.
21 citations
,
May 2001 in “PubMed” This paper reviews the significance of androgen hormones in hair and skin conditions like alopecia, hirsutism, and acne, and reports no new clinical findings.
19 citations
,
December 1985 in “Journal of The American Academy of Dermatology” Minoxidil can cause scalp comedones and acne.
14 citations
,
December 2003 in “Medical Hypotheses” This paper proposes a new hypothesis that androgenic hair loss may be caused by changes in scalp vasculature due to androgen effects, but reports no new experimental results.
12 citations
,
May 1989 in “Postgraduate Medicine” This article discusses treatments for male pattern baldness, noting that minoxidil is effective for improving baldness at the scalp vertex in young men, and reports no new clinical results.
8 citations
,
June 2011 in “Nature Biotechnology” Stem cell treatments can potentially treat baldness, with one trial showing hair growth after injecting a hair-stimulating complex, and no safety issues were reported.
6 citations
,
May 2020 in “Scientific reports” In this study, microarray and proteomic analyses indicated that genes involved in immune response, receptor binding, and growth factor activity might influence wool fibre diameter in sheep.
6 citations
,
February 2020 in “Journal of Natural Products” In this chemical investigation, cyclospongiaquinone 1 from the sponge Verongula cf. rigida showed strong steroid 5α-reductase inhibitory activity, comparable to that of finasteride.
3 citations
,
January 1999 in “PubMed” This review discusses the societal impact and treatment development for androgenetic alopecia, highlighting promising new drugs but reporting no new clinical results.
2 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This review discusses unique anatomical features and management strategies for crown alopecia but reports no new clinical findings, focusing instead on surgical techniques for natural-looking results and optimal density.
2 citations
,
January 2004 in “Enshou saisei” This study suggests that beard dermal papilla cells may produce androgen-dependent growth factors that stimulate keratinocyte proliferation, while frontal scalp cells can have an inhibitory effect mediated by TGF-β1.
1 citations
,
January 1995 in “Journal of Investigative Dermatology” RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.
November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that the leaf extract of Tectona grandis and its major bioactive constituents moderately inhibit the 5α-reductase enzyme, which is linked to androgenetic alopecia, and also possess anti-inflammatory properties, showing promise as dual-action candidates for managing this condition.
August 2009 in “Journal of Oral and Maxillofacial Surgery” This review discusses the concept of "Donor Dominance" in hair transplantation, initially introduced by Dr. Norman Orentreich, and reports no new clinical results.
January 1992 in “Juntendo Medical Journal” This article discusses male pattern baldness and the potential of androgen inhibitors, reporting on previous findings and the need for new preventive measures; it does not present new clinical results.
This review discusses the genetic and hormonal factors involved in androgenetic alopecia but reports no new research findings.
January 2014 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” This article discusses androgenetic alopecia, including its prevalence, different patterns in men and women, and variations among races, without providing new clinical findings.
July 2013 in “e-Jurnal Medika Udayana” This article discusses the impact of estrogens on hair follicle growth in female pattern hair loss, noting their ability to increase anagen phase and suppress telogen phase, but reports no new clinical results.
June 1996 in “Archives of Dermatology” Using a mix of finasteride and minoxidil can significantly regrow hair in men with pattern baldness.
107 citations
,
May 1999 in “Archives of Dermatological Research” In this study, the immunohistochemical and lectin binding profiles of basal cell carcinoma closely resembled those of the outer root sheath of vellus hair follicles, suggesting a potential histochemical relationship.
58 citations
,
January 2006 in “Skin Pharmacology and Physiology” This study found that testosterone and 5α-dihydrotestosterone induced apoptosis in dermal papilla cells from nonbalding scalp regions, suggesting a high androgen stimulus can trigger cell death related to androgenetic alopecia.
51 citations
,
January 2003 in “Hormone Research in Paediatrics” This review discusses hormonal influences on hair growth and suggests that understanding hormone-gene interactions may improve treatment of hirsutism and alopecia, but reports no new clinical findings.
19 citations
,
January 2009 in “International review of cell and molecular biology” This review explains the mechanical composition and molecular interactions that determine hair's mechanical properties, without providing any new experimental findings.
April 2021 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism” This study reports a case of Cushing disease caused by a rare giant pituitary macroadenoma in a 41-year-old woman, requiring additional treatment after unsuccessful surgery.
January 2004 in “Kölner Universitäts PublikationsServer (Universität zu Köln)” This study suggests that CD151-integrin complexes inhibit epithelial cell migration, and that disruption of these complexes enhances migration, regulated by Rho GTPase activation differences on distinct laminins.
January 2022 in “Springer eBooks” The book explains causes and treatments for common hair loss, its psychological effects, related health risks, and emphasizes early screening and lifestyle changes.
January 2026 in “Dermatologic Therapy” This review found that circulating dihydrotestosterone (DHT) consistently distinguishes men with androgenetic alopecia from controls, suggesting a key role in the condition's biology and potential therapeutic targeting.