23 citations
,
December 1991 in “Annals of the New York Academy of Sciences” This study reported that human balding scalp grafted onto nude mice showed reduced linear growth rates of both vellus and terminal hairs.
21 citations
,
November 2017 in “Scientific Reports” This study found that prostaglandin D2 reduced proliferation in bulge resident K15+ stem cells but not in other K15+ progenitor cells, suggesting differential impacts on hair follicle stem cell niches.
20 citations
,
August 2016 in “International Journal of Cancer” This study reports that male-pattern baldness may be linked to an increased risk of skin cancer, particularly for tumors located on the scalp.
19 citations
,
January 2001 in “Dermatology + psychosomatics” This review discusses the perceptions of male pattern baldness by strangers and explores the sociocultural aspects of hair and hair loss but reports no new results.
9 citations
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November 1993 in “Journal of The American Academy of Dermatology” Some men can have female pattern baldness without hormonal abnormalities or signs of feminization.
4 citations
,
January 2000 in “PubMed” In this study, researchers found that young men with premature androgenetic alopecia had a hormonal profile similar to the pattern seen in women with polycystic ovary syndrome, suggesting a possible genetic link.
2 citations
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January 2009 in “Journal of the Royal Society of Medicine” This article reviews depictions of baldness in art and notes its symbolic connections to depression, with no new research findings presented.
The research examined Crown-X, a novel formulation containing Menstrual Stem Cells, and found that it promoted significant proliferation of human dermal papilla cells, suggesting its potential as a non-invasive treatment for male pattern baldness. Future clinical trials are necessary to confirm its efficacy.
January 2011 in “Yearbook of Dermatology and Dermatologic Surgery” Moles on the scalp are more common in people with more body moles and atypical moles, but not linked to balding.
58 citations
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June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that Atlantic croaker nuclear androgen receptors AR1 and AR2 have different binding affinities for androgens, suggesting that they may mediate distinct physiological actions in teleosts.
39 citations
,
January 2004 in “Physiological Research” In this study, researchers reported that about one-third of men with premature alopecia displayed hormonal shifts and higher insulin resistance, resembling the prevalence pattern of PCOS in women.
22 citations
,
September 2001 in “Journal of Investigative Dermatology” S100A8 and S100A9 proteins help form hair shafts during growth.
1 citations
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September 1997 in “PubMed” In this report, the authors suggest that for extensive baldness, the uniform density approach in hair restoration surgery is less noticeable, especially in situations like wind or exercise.
March 2017 in “Journal of Dermatology” This article is a letter discussing variations in male sex hormone levels among different pattern subtypes of androgenetic alopecia and does not present new research results.
46 citations
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December 2001 in “Journal of Endocrinology/Journal of endocrinology” This study found that mouse FLRG protein, a secreted glycoprotein, is expressed in certain tissues and plays a role distinct from follistatin during wound healing, suggesting different functions in vivo.
1 citations
,
January 2016 in “Asian-Australasian journal of animal sciences” In this study, the expression of Gnαs was significantly higher in black mice compared to white mice, suggesting its potential involvement in coat color formation in mice.
15 citations
,
May 2016 in “Archives of Dermatological Research” This study found significantly higher levels of the protein ULBP3 in patients with alopecia areata incognita compared to other hair loss conditions and healthy controls, suggesting ULBP3's potential as a diagnostic marker for AAI.
January 1990 in “대한피부과학회지” This study found that peanut agglutinin binding patterns after neuraminidase pretreatment can help differentiate malignant melanoma from nevocellular nevus in skin specimens.
4 citations
,
November 2017 in “Cancer Causes & Control” This study found that men with androgenetic alopecia at age 20 years may have a higher risk of developing aggressive prostate cancer, particularly advanced stage disease.
159 citations
,
July 2006 in “Endocrine Reviews” This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.
24 citations
,
January 2010 in “Endocrine Regulations” In this study, men taking 1 mg/day of finasteride for 12 months showed minor metabolic changes and slight improvements in glucose metabolism.
1 citations
,
August 2024 in “Indian Dermatology Online Journal” In this study, bicalutamide showed promise in managing female pattern hair loss and reducing minoxidil-induced hypertrichosis, though further research is necessary to refine its use and establish its role in treatment.
1 citations
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April 2016 in “Journal of Investigative Dermatology” This study identified that blocking the PTGDR2 receptor in human hair follicles in vitro and in mice reversed the hair growth inhibition caused by PGD2, suggesting a potential approach for treating alopecia.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This paper introduces the Vertex Overload Framework for androgenetic alopecia, suggesting that chronic mechanical and thermal stress on the vertex contributes to hair follicle miniaturization, with androgens acting as co-mediators of stress adaptation rather than isolated causes.
December 2024 in “Routledge eBooks” In this study, the author explores ancient Egyptian attitudes towards male pattern baldness through interdisciplinary and biblical feminist perspectives, revealing that baldness was recognized as unattractive yet also associated with respect for older men's work ethic and masculinity.
This study found that 2-hydroxy-1,4-naphthoquinone was the most effective inhibitor of steroid 5α-reductase, showing stronger inhibition than avicequinone C in HaCaT cell assays.
July 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” This source discusses the characteristics and clinical presentation of androgenetic alopecia, emphasizing the importance of early recognition and grading for administering therapy and the role of trichoscopy in diagnosis and monitoring treatment response.
19 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article discusses the evolution and variation of hairlines in men and women across different ages, introducing a modeling system to standardize the anatomical description of hairlines, without reporting new experimental findings.
17 citations
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December 2004 in “The Journal of Men's Health & Gender” This article discusses the role of androgens in hair follicle changes, explaining how dihydrotestosterone contributes to hair thinning on the scalp, while promoting thicker facial hair in men, and reports no new clinical results.
May 2004 in “Facial Plastic Surgery Clinics of North America” Better understanding of hair patterns and advanced techniques are crucial for improving hair restoration and removal outcomes.