13 citations
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September 2011 in “Archives of dermatology” This case report describes a 3-year-old male with X-linked ichthyosis and associated neurologic abnormalities, identifying an unusual cortical development malformation and suggesting that abnormal hair banding may assist diagnosis.
In this study conducted at Saveetha Dental College, researchers found that the severity of male androgenetic alopecia, as graded by Norwood's classification, increased with age, although other factors such as genetic or hormonal influences were not assessed.
June 2024 in “Archives of Dermatological Research” In this study, significant upregulation of the genes SFRP2 and PTGDS was found in bald hair follicles of female pattern hair loss patients compared to non-bald follicles, suggesting these genes may be biomarkers and play a role in hair loss for this condition.
51 citations
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January 1989 in “Journal of Investigative Dermatology” This study found that sebaceous glands in bald scalp have greater androgen binding affinity and capacity than those in hairy scalp, possibly contributing to the androgenic response seen in male pattern baldness.
32 citations
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December 2004 in “BMC Public Health” This study found that trained observers using the Hamilton-Norwood classification were very reliable in assessing balding patterns, while men's self-assessments were moderately accurate compared to observers.
March 2022 in “Journal of The American Academy of Dermatology” This study characterized the incidence of hair loss patterns among men of different races, highlighting a lack of direct racial comparisons in previous research.
October 2023 in “Acta dermato-venereologica” Minoxidil and platelet-rich plasma can help turn thin hair into thicker hair in male pattern baldness.
November 2015 in “Hair transplant forum international” This abstract discusses a randomized trial comparing rosemary oil and minoxidil 2% for treating androgenetic alopecia, but it reports no new clinical results; the authors mention ongoing research.
November 2022 in “Journal of Investigative Dermatology” This study suggests that vellus to terminal hair follicle reconversion can occur in male pattern androgenetic alopecia using an in vivo model with minoxidil and platelet-rich plasma treatment.
29 citations
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October 2011 in “British Journal of Dermatology” This study found that four microRNAs, which were significantly upregulated in balding hair follicle papilla cells, could play a role in the development of male pattern baldness.
13 citations
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September 1986 in “Archives of Dermatology” This study found that women with female pattern baldness often had a higher ratio of 3 alpha,17 beta-androstanediol glucuronide to sex hormone-binding globulin and lower serum sex hormone-binding globulin, possibly indicating minimal androgen excess.
February 2024 in “Research Square (Research Square)” This study identified SFRP2 and PTGDS as potential biomarkers for female pattern hair loss, finding these genes consistently upregulated in bald hair follicles from all 18 patients, which may contribute to understanding the condition's pathogenesis and developing targeted treatments.
September 1989 in “PubMed” This study found no significant differences in sex-hormone binding globulin and androgen serum levels between women with stage II androgenetic alopecia and controls, suggesting that genetically-determined androgen sensitivity might play a major role in the condition.
46 citations
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June 1983 in “Cleveland Clinic Journal of Medicine” In this study, women with diffuse alopecia were found to have higher serum levels of adrenal androgen DHEAS, which may contribute to disrupted scalp hair growth.
38 citations
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November 2005 in “Journal of Investigative Dermatology Symposium Proceedings”
29 citations
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July 2020 in “Journal of The American Academy of Dermatology” In this study, researchers found that severe androgenic alopecia in hospitalized men was associated with a higher likelihood of testing positive for COVID-19.
13 citations
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May 2004 in “Facial Plastic Surgery Clinics of North America” This article discusses the significance of anatomic zones in hair loss and underscores the importance for hair restoration surgeons to understand these patterns and their implications for future treatments, but reports no new clinical findings.
8 citations
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April 2001 in “Dermatologic Surgery” This proposal presents a standardized system for naming areas of the balding scalp to improve communication among hair restoration professionals, defining major regions and introducing new landmarks.
7 citations
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March 2005 in “British Journal of Dermatology” This study discusses patterns of androgenetic alopecia in Indian men but reports no new clinical findings.
68 citations
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February 1990 in “Journal of Applied Social Psychology” This study found that men with common male pattern baldness received less favorable initial social perceptions, including lower ratings of physical attractiveness, than their nonbalding counterparts.
5 citations
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February 2015 in “Dermatologica Sinica” In this study, a computer-aided imaging system accurately measured the width of balding areas in female pattern hair loss, correlating strongly with clinical staging severity.
September 2015 in “Dermatologic Surgery” In this study, the researchers developed a computer-aided imaging system to quantitatively measure baldness in Chinese women with female pattern hair loss, potentially improving the precision of severity evaluation compared to traditional scales.
227 citations
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January 1998 in “Journal of Endocrinology” This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.
25 citations
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May 1986 in “The American Journal of the Medical Sciences” In this study, 53% of patients with male pattern baldness experienced significant hair growth with one year of topical minoxidil, while 95% rated its effectiveness as moderate or excellent.
19 citations
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February 2008 in “Archives of Dermatological Research” This study observed that mast cells and increased collagen and elastic fibers in the scalp may contribute to male pattern hair loss, but additional research is needed for further understanding.
2 citations
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July 2018 in “Journal of Cosmetic Dermatology” This commentary discusses how common latent viruses might contribute to male-pattern baldness through mechanisms involving transcription factor deficiency and overexpression of specific proteins, based on a concept called microcompetition; it reports no new research results.
26 citations
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June 2000 in “Journal of The American Academy of Dermatology” This study found that older men with vertex balding had lower levels of IGFBP-3 and higher levels of IGF-1 in their plasma.
3 citations
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June 2000 in “Journal of The American Academy of Dermatology” This study found that older men with vertex balding have lower circulating levels of the protein IGFBP-3 and higher levels of IGF-1.
2 citations
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October 2020 in “Journal of The American Academy of Dermatology” This research discusses androgenic alopecia's potential role in severe COVID-19 symptomatology and suggests further exploration of the scalp's role in virus transmission.
29 citations
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February 2004 in “Experimental and Clinical Endocrinology & Diabetes” This study suggests that many men with premature balding exhibit a hormonal pattern similar to some aspects of polycystic ovary syndrome in women.