83 citations
,
March 2015 in “International Journal of Dermatology” This retrospective study found that adipose-derived stem cell-conditioned media increased hair density and thickness in women with female pattern hair loss over 12 weeks, with no severe adverse effects reported.
51 citations
,
March 1987 in “Journal of The American Academy of Dermatology” This study found that twice-daily application of 3% topical minoxidil maintained a higher nonvellus hair count compared to once-daily application over 2 years and 9 months in men with male pattern baldness.
47 citations
,
August 2011 in “Journal of The European Academy of Dermatology and Venereology” This study found that treatment with a 1550 nm fractional erbium–glass laser increased hair density and thickness in women with female pattern hair loss, suggesting it may be an effective and safe option.
43 citations
,
April 2017 in “Experimental Dermatology” This review summarizes the genetic studies on female pattern hair loss, highlighting the lack of clearly identified susceptibility loci and suggesting distinct aetiological differences from male pattern hair loss.
32 citations
,
March 2020 in “Drug Design Development and Therapy” This review examines the pharmacology, clinical efficacy, and adverse effects of oral finasteride for female pattern hair loss, and discusses potential new treatments like topical finasteride and dutasteride, but reports no new clinical results.
31 citations
,
October 2005 in “British Journal of Dermatology” This study found that sebum excretion is not increased in women with female pattern hair loss, suggesting nonandrogenic factors may contribute to hair loss in some women without hirsutism.
31 citations
,
January 1989 in “Clinical and Experimental Dermatology” In this study, topical 2% minoxidil did not significantly improve hair density measures in men with male pattern baldness, although there was no deterioration, suggesting a potential prophylactic effect.
21 citations
,
August 2013 in “Journal of Dermatological Treatment” This review discusses the mixed evidence and high risk of bias in studies on low-level light therapy for treating androgenetic alopecia and calls for rigorous randomized controlled trials to assess its efficacy.
19 citations
,
August 2000 in “International Journal of Dermatology” This article discusses the medical management of male pattern hair loss and reports no new clinical findings.
13 citations
,
October 2011 in “Clinical and Experimental Dermatology” This study found no improvement in male-pattern hair loss after six months of using laser hair-comb therapy in two men.
13 citations
,
October 2002 in “Journal of Biochemical and Biophysical Methods” This study found that men with androgenic alopecia had significantly higher levels of certain urinary steroid metabolites, suggesting increased 5 alpha-reductase activity and possible mild hyperadrenal activity.
10 citations
,
September 2020 in “Archives of Dermatological Research” Both methods improve hair density and thickness; double-spin may be more effective.
4 citations
,
April 2020 in “Journal of Cosmetic Dermatology” This study found that Chinese patients with alopecia areata, female pattern hair loss, and male androgenetic alopecia had significantly lower serum vitamin D levels than healthy individuals.
3 citations
,
April 2010 in “Endocrinology” This review discusses the mechanisms of androgenic alopecia and reports no new results; the development of a mouse model for further study is described.
2 citations
,
June 2011 in “Expert Review of Dermatology” This review discusses the characteristics and management options for female pattern hair loss, highlighting the unclear role of androgens and the psychosocial impact, and reports no new clinical results.
August 2024 in “IAHS Medical Journal” This study, conducted among 50 women with female-pattern hair loss, observed that 89% had deficient or insufficient vitamin D levels and also showed low ferritin levels, suggesting these deficiencies may contribute to hair loss.
Botulinum toxin injections can reduce hair loss and stimulate new hair growth in some men with male pattern baldness.
April 2019 in “Journal of emerging technologies and innovative research” This article discusses female pattern baldness and effective treatments like oral anti-androgens and topical minoxidil for managing its progression and reversing hair follicle shrinkage, but reports no new findings.
August 2002 in “Zeitschrift für Hautkrankheiten” This review discusses female pattern hair loss, suggesting it involves both androgen-dependent and independent factors, but it reports no new clinical results.
58 citations
,
July 1986 in “Journal of The American Academy of Dermatology” Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.
37 citations
,
October 2015 in “European Journal of Human Genetics” This study found that a genetic model using SNPs can predict early-onset male-pattern baldness with moderate accuracy, which may assist in decisions about interventions.
28 citations
,
September 2014 in “Journal of Clinical Oncology” This study observed that frontal plus moderate vertex baldness at age 45 was associated with a higher risk of aggressive prostate cancer in a large cohort.
16 citations
,
October 2012 in “The Journal of Dermatology” This study found that the BASP classification system for pattern hair loss showed better reproducibility and repeatability compared to the Norwood-Hamilton classification.
57 citations
,
November 2017 in “Nature Communications” This genome-wide association study identified 71 genetic loci linked to male pattern baldness, with 30 novel loci, explaining 38% of the risk and suggesting shared pathways with lifespan and cancer traits.
15 citations
,
July 2020 in “Dermatologic Therapy” This review discusses the pathophysiology, diagnosis, systemic associations, and treatments for female pattern hair loss and reports no new clinical findings.
215 citations
,
November 2006 in “Journal of The American Academy of Dermatology” This study found that dutasteride increased scalp hair growth in men with male pattern hair loss, particularly at a 2.5 mg dose, and was more effective than finasteride over 24 weeks.
203 citations
,
December 2004 in “Journal of The American Academy of Dermatology” This article reviews the historical developments in understanding and treating male pattern hair loss, emphasizing the role of dihydrotestosterone and 5α-reductase inhibitors, but reports no new clinical findings.
133 citations
,
February 2017 in “PLoS Genetics” In this study, researchers used genetic data from over 52,000 men to identify over 250 genetic loci associated with severe hair loss and developed a predictive algorithm for determining hair loss risk.
87 citations
,
March 2011 in “Australasian Journal of Dermatology” This review explores the current understanding of genetic and hormonal influences on male androgenetic alopecia and female pattern hair loss, providing guidance for clinicians but reports no new results.
72 citations
,
January 2004 in “Dermatology” This study found that oral finasteride, at a dosage of 2.5 mg/day or more, may improve hair growth and appearance in postmenopausal women with pattern hair loss, without adverse effects.