The Use of Botulinum Toxin in the Treatment of Male Pattern Baldness

    May 2013 in “ Toxicon
    Brian Freund, Marvin Schwartz
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    TLDR Botulinum toxin injections can reduce hair loss and stimulate new hair growth in some men with male pattern baldness.
    In a study conducted 10 years ago, 50 male subjects aged between 19 and 57 years with Norwood/Hamilton ratings of II to IV were treated with peripheral scalp injections of botulinum toxin-A (BTX-A) to determine if it would reduce hair loss or stimulate hair growth. The 60-week study showed a response rate of 75% with 40 subjects completing the study. The mean hair counts for the entire group showed a statistically significant increase of 18% between baseline and week 48, similar to the results reported with Propecia®. Hair loss was reduced by 39%. The study concluded that strategically placed BTX-A injections appear able to indirectly modify scalp physiology, resulting in reduced hair loss and new hair growth in some men with androgenetic alopecia.
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