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Treatment of Male Rats with Finasteride, an Inhibitor of 5alpha-Reductase Enzyme, Induces Long-Lasting Effects on Depressive-Like Behavior, Hippocampal Neurogenesis, Neuroinflammation, and Gut Microbiota Composition

research Treatment of Male Rats with Finasteride, an Inhibitor of 5alpha-Reductase Enzyme, Induces Long-Lasting Effects on Depressive-Like Behavior, Hippocampal Neurogenesis, Neuroinflammation, and Gut Microbiota Composition

37 citations, September 2018 in “Psychoneuroendocrinology”

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

research Platelet-Derived Growth Factor Signaling Modulates Adult Hair Follicle Dermal Stem Cell Maintenance and Self-Renewal

37 citations, April 2017 in “npj Regenerative Medicine”

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

research Recent Advances in Thiasteroids Chemistry

37 citations, October 2006 in “Steroids”

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

research Photobiomodulation Devices for Hair Regrowth and Wound Healing: A Therapy Full of Promise but a Literature Full of Confusion

36 citations, April 2016 in “Experimental Dermatology”

Photobiomodulation may help with hair growth and wound healing, but research is inconsistent and needs better quality studies.

Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse

research Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse

36 citations, April 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Testosterone Improves Antidepressant-Emergent Loss of Libido in Women: Findings from a Randomized, Double-Blind, Placebo-Controlled Trial

research Testosterone Improves Antidepressant-Emergent Loss of Libido in Women: Findings from a Randomized, Double-Blind, Placebo-Controlled Trial

36 citations, January 2014 in “The Journal of Sexual Medicine”

Testosterone may help increase sexual events for women with low libido due to antidepressants.

Single-Cell Transcriptomic Analysis of Small and Large Wounds Reveals the Distinct Spatial Organization of Regenerative Fibroblasts

research Single-Cell Transcriptomic Analysis of Small and Large Wounds Reveals the Distinct Spatial Organization of Regenerative Fibroblasts

35 citations, November 2020 in “Experimental Dermatology”

Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.

research Fibromodulin Reduces Scar Formation in Adult Cutaneous Wounds by Eliciting a Fetal-Like Phenotype

35 citations, October 2017 in “Signal Transduction and Targeted Therapy”

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.

research A Review of Adipocyte Lineage Cells and Dermal Papilla Cells in Hair Follicle Regeneration

35 citations, January 2014 in “Journal of Tissue Engineering”

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

Minoxidil Improves Vascular Compliance, Restores Cerebral Blood Flow, and Alters Extracellular Matrix Gene Expression in a Model of Chronic Vascular Stiffness

research Minoxidil Improves Vascular Compliance, Restores Cerebral Blood Flow, and Alters Extracellular Matrix Gene Expression in a Model of Chronic Vascular Stiffness

34 citations, July 2018 in “American Journal of Physiology-heart and Circulatory Physiology”

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin

34 citations, February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Cell Wall-Associated Root Hair Specific 10, a Proline-Rich Receptor-Like Kinase, Is a Negative Modulator of Arabidopsis Root Hair Growth

research Cell Wall-Associated Root Hair Specific 10, a Proline-Rich Receptor-Like Kinase, Is a Negative Modulator of Arabidopsis Root Hair Growth

33 citations, February 2016 in “Journal of Experimental Botany”

ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.

research Hair Restoration Surgery: The State of the Art

32 citations, November 2012 in “Aesthetic Surgery Journal”

Hair restoration surgery has advanced, focusing on natural results and may improve further with new techniques and therapies.

The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target

research The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target

32 citations, January 2012 in “Clinical & Developmental Immunology”

Targeting CD200 could be a new treatment for rheumatoid arthritis.

research Effects of Curcumin on Glycemic Control and Lipid Profile in Polycystic Ovary Syndrome: Systematic Review with Meta-Analysis and Trial Sequential Analysis

31 citations, February 2021 in “Nutrients”

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

research Use of Extracellular Matrix Hydrogel from Human Placenta to Restore Hair-Inductive Potential of Dermal Papilla Cells

31 citations, August 2019 in “Regenerative Medicine”

Human placenta hydrogel helps restore cells needed for hair growth.

Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine

research Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine

31 citations, February 2019 in “International Journal of Cosmetic Science”

Caffeine applied to the scalp can protect hair follicles from UV damage.

research MicroRNAs in the Skin: Role in Development, Homeostasis, and Regeneration

31 citations, July 2017 in “Clinical Science”

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

research Touch Receptors Undergo Rapid Remodeling in Healthy Skin

31 citations, November 2016 in “Cell Reports”

Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.

research Signaling Couples Hair Follicle Stem Cell Quiescence With Reduced Histone H3 K4/K9/K27me3 for Proper Tissue Homeostasis

31 citations, April 2016 in “Nature communications”

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.