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Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.

The conclusion is that certain physical signs in the body can indicate past acute and chronic stress, which may help in child abuse investigations.

A pet ferret had a serious infection from Mycobacterium xenopi, which can spread to humans.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

Trichoscopy is a useful tool for diagnosing different hair and scalp diseases without surgery.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.

Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.

A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.

Using old drugs for new uses can help treat rare immune deficiencies.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The exam tested knowledge on various skin-related topics for CME credit.

Both topical calcipotriol and narrowband UVB improved alopecia, but combining them didn't enhance the effect on hair loss severity, despite higher vitamin D3 levels.

A specific genetic change is linked to mental disorders, intellectual disability, and possibly autoimmune disease in a family.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Follicular mycosis fungoides can look like a B-cell lymphoma, making diagnosis difficult.

A 69-year-old smoker was wrongly diagnosed with lung cancer but actually had a rare lymphatic system disorder.

A woman's hair loss, resembling an autoimmune condition, improved after treatment, but requires ongoing checks due to potential serious associations.

Controlling Tslp can improve health in AEC syndrome patients.

A woman with severe angioedema improved significantly after treatment with rituximab.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Hormone-replacement therapy improved a woman's skin condition known as lymphomatoid papulosis.

A man had rare skin tumors with bone formation and cholesterol deposits.

Human scalp hair follicles can be used to study how prolactin affects hair growth and cell death.