Utilizing the Hair Follicle to Dissect the Regulation and Autocrine/Paracrine Activities of Prolactin in Humans

    May 2012 in “ Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism ”
    Ewan A. Langan, C.E.M. Griffiths, Ralf Paus
    Studysummary This article discusses the potential of using human hair follicles as a model to study prolactin's regulation and activities but reports no new experimental findings; the authors suggest further research in this area.
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    Research cited in this study 8

    1. Endocannabinoids Limit Excessive Mast Cell Maturation And Activation In Human Skin Journal of Allergy and Clinical Immunology · 2012
    2. Prolactin: An Emerging Force Along the Cutaneous–Endocrine Axis Trends in Endocrinology and Metabolism · 2010
    3. Thyrotropin-Releasing Hormone and Estrogen Differentially Regulate Prolactin and Prolactin Receptor Expression in Female Human Skin and Hair Follicles In Vitro British Journal of Dermatology · 2010
    4. Prolactin: A Novel Neuroendocrine Regulator of Human Keratin Expression In Situ The FASEB Journal · 2010
    5. Mind the Gender Gap: Does Prolactin Exert Gender and Site-Specific Effects on the Human Hair Follicle? Journal of Investigative Dermatology · 2009
    6. Methods in Hair Research: How to Objectively Distinguish Between Anagen and Catagen in Human Hair Follicle Organ Culture Experimental Dermatology · 2009
    7. Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, Which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression American Journal of Pathology · 2006
    8. Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen American Journal of Pathology · 2003