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research Androgen-Dependent Beard Dermal Papilla Cells Secrete Autocrine Growth Factors in Response to Testosterone Unlike Scalp Cells

51 citations , November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.

To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease

research To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease

23 citations , April 2016 in “American Journal of Pathology”

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

research Utilizing the Hair Follicle to Dissect the Regulation and Autocrine/Paracrine Activities of Prolactin in Humans

12 citations , May 2012 in “Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism”

Human scalp hair follicles can be used to study how prolactin affects hair growth and cell death.

research Hair Dermal Papilla Maintain Its Hair Inducing Characteristics Via Autocrine Exosomal miR-23a-3p

July 2025

Hair growth is maintained by specific cell signals.

research An Immunohistochemical Study of the Apocrine Type of Cutaneous Mixed Tumors with Special Reference to Their Follicular and Sebaceous Differentiation

54 citations , May 1999 in “Journal of Cutaneous Pathology”

Apocrine type cutaneous mixed tumors often resemble hair follicles, sebaceous glands, and apocrine glands.

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community does lowering your prolactin levels regrow hair?

in Research/Science 10 upvotes 3 years ago

The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

community Does lowering serum prolactin lower prolactin in the scalp?

in Research/Science 13 upvotes 2 years ago

The conversation discusses whether not masturbating (semen retention) affects hair loss, with opinions varying but generally dismissing the idea. Some participants mention using hair loss treatments like Minoxidil, Finasteride, and RU58841, but the effectiveness and relation to prolactin levels in the scalp are debated.

community Why HMI115 should work if it doesn’t affect dht?

in Research/Science 16 upvotes 2 years ago

Hair growth can be induced without stopping DHT, as seen with Minoxidil. HMI115 may work by promoting follicle growth, not targeting the root cause of hair loss (DHT).

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 1 month ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community 23M diffuse thinner: 3 months difference - We are so back

in Progress Pictures 1956 upvotes 7 months ago

A 23-year-old male showed hair regrowth after using finasteride and minoxidil daily for three months, with no significant side effects. Others shared their experiences and discussed side effects and photo lighting differences.

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