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The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

A mutation in the HR gene causes a rare form of irreversible hair loss in two Kashmiri families. Whole exome sequencing is effective for finding such mutations.

The document concludes that an experimental drug may help wound healing in Epidermolysis Bullosa, links Hydroa vacciniforme to EBV, discusses diagnosing hair loss disorders, finds many children with eczema have allergies, reviews the safety of a skin medication in children, notes side effects of a Duchenne's treatment, and identifies a marker for pediatric mastocytosis.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.

Finasteride helps hair growth but may cause sexual side effects.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Hair loss in men treated best with early medication or transplant, new treatments researched.

The conclusion is that an algorithm using trichoscopy helps diagnose different types of hair loss but may need updates and a biopsy if results are unclear.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

FFA's causes may include environmental triggers and genetic factors.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

The most common skin problems in Indian children are infections and eczemas.

Notch-related genes play a key role in the development and cycling of hair follicles.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

KFSD is a rare condition causing scarring hair loss, with no effective treatment known at the time of the report.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

The study suggests smoking is common in HS patients but its role is unclear, and more research is needed to understand HS causes.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.