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Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

A specific gene variant is linked to a higher risk of hair loss from chemotherapy in breast cancer patients.

Genetic discoveries are leading to new treatments for alopecia areata.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.

A complex X chromosome rearrangement can increase the risk of multiple autoimmune diseases.

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

Zinc is crucial for skin health and treating various skin disorders.

Some women with PCOS have rare genetic variants linked to the condition.

No significant link between male pattern baldness and COVID-19 severity was found.

Familial frontal fibrosing alopecia is rare, mostly affects women, and often occurs between sisters or mother-daughter pairs.

Certain DNA regions in alpacas are linked to fiber diameter.

Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

The research found specific genes and pathways that control fur development and color in young American minks.

Afro-textured hair needs personalized care due to its unique genetic traits.

Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.

Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.

Hoxc13 gene affects wool length in Gansu alpine fine-wool sheep.

People with common hair loss conditions may have a higher risk of heart disease and related health issues.

DNA markers can help predict male pattern baldness, useful in criminal and missing person cases.

Men with a family history of hair loss on their mother's side are more likely to have female pattern hair loss.

A mother's iron levels early in pregnancy can influence the DNA makeup of her child, potentially affecting the child's health.

Increasing research diversity is key for better understanding and treating Parkinson's Disease.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Protein profiling of forehead skin can help distinguish between frontal fibrosing alopecia and androgenetic alopecia.