34 citations,
February 2018 in “Drug Design Development and Therapy” Bimatoprost is safe and effective for improving eyebrow hair.
34 citations,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
34 citations,
July 2010 in “Expert Opinion on Drug Delivery” The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
32 citations,
January 2021 in “Molecules” Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.
30 citations,
May 2016 in “Expert Opinion on Biological Therapy” New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
28 citations,
August 2015 in “Journal of functional biomaterials” Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.
27 citations,
January 2020 in “Experimental Dermatology” Immune cells affect hair growth and could lead to new hair loss treatments.
27 citations,
May 2010 in “Dermatologic surgery” Photodynamic therapy with methyl 5-aminolevulinic acid is ineffective for treating alopecia totalis.
26 citations,
May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
26 citations,
February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
25 citations,
May 2003 in “Expert Opinion on Therapeutic Patents” Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
25 citations,
July 1991 in “International Journal of Dermatology” Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.
24 citations,
May 2016 in “Stem Cell Reviews and Reports” The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
24 citations,
November 2013 in “Trends in pharmacological sciences” Increasing ABC transporters in hair follicles may prevent chemotherapy-induced hair loss.
23 citations,
December 2020 in “Frontiers in Cell and Developmental Biology” Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
23 citations,
October 2018 in “Expert Opinion on Drug Safety” Consider benefits and risks of new alopecia treatments for safety.
22 citations,
November 2014 in “Psychiatric Clinics of North America” Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.
17 citations,
June 2020 in “Animals” lncRNAs may regulate hair follicle development in Hu sheep.
17 citations,
February 2019 in “PubMed” Stem cells can help regenerate hair follicles.
17 citations,
December 2001 in “Dermatologic therapy” Different treatments for alopecia areata have unpredictable results and varying success rates.
16 citations,
December 2012 in “The Clinical Journal of Pain” Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.
15 citations,
June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
15 citations,
October 2012 in “InTech eBooks” Niosomes are a promising and effective way to deliver drugs through the skin.
15 citations,
November 1994 in “International Journal of Dermatology” Propranolol combined with injections caused skin changes in guinea pigs but didn't fully mimic psoriasis.
14 citations,
January 2018 in “Advances in Clinical Chemistry” The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
13 citations,
January 2014 in “Dermatology” Radiation-induced alopecia after angioembolization usually heals on its own and can look like other hair loss types, but patient history helps prevent misdiagnosis.
11 citations,
September 2021 in “Journal of molecular endocrinology” ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
11 citations,
July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
10 citations,
June 2019 in “International Journal of Cosmetic Science” Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
10 citations,
January 2018 in “Postępy Dermatologii i Alergologii” Treating alopecia areata every 3 weeks with diphenylcyclopropenone is more effective than weekly treatments.