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This study found that C3H mice with prior microbial exposure developed alopecia areata at a reduced rate and had fewer associated T cells compared to controls, suggesting that prior infections might attenuate autoimmune responses related to the disease.

This study found that patients with alopecia areata had significantly lower frequencies of IL-10 producing CD19+CD24hiCD38hi regulatory B cells compared to healthy volunteers, suggesting a potential role for these cells in the autoimmune response seen in the condition.

Enhancing regulatory T cells may help treat autoimmune diseases like alopecia areata.

This study developed an animal model that recreates alopecia areata by injecting healthy human skin grafts in immunocompromised mice with peripheral blood mononuclear cells enriched for NKG2D+ and CD56+ cells.

In this case report, a woman developed severe alopecia areata approximately one year after starting belimumab for systemic lupus erythematosus, with hair loss improving upon discontinuation of the drug, suggesting a possible connection between belimumab and immune-mediated hair loss.

This study reported that the anti-γc antibody hC2 restored hair follicle homeostasis and suppressed hair loss in an AA-like mouse model by inhibiting autoreactive T-cell activity, suggesting that hC2 may offer a safer and more effective treatment for alopecia areata compared to current Jak inhibitors.

This study identified key genetic regions associated with alopecia areata, highlighting both acquired and innate immune involvement, with a novel link to the upregulation of ULBP ligands in autoimmune disease.

This study found that the R257X mutation in the AIRE gene is prevalent among Russian patients with autoimmune polyglandular syndrome type 1, particularly in those with hypoparathyroidism and chronic mucocutaneous candidiasis.

Specific immune cells cause alopecia areata and blocking certain proteins can prevent it.

This study reports two cases of Alopecia Universalis as a secondary autoimmune manifestation following Alemtuzumab treatment, highlighting the importance of screening and monitoring for such autoimmune responses.

This study found that ILC1-like cells can induce alopecia areata in healthy human hair follicles, suggesting that these cells might be a therapeutic target in AA management.

This study found distinct gene expression patterns in the blood of alopecia areata patients, suggesting involvement of immune processes and new pathways like Wnt signaling and apoptosis in disease pathogenesis.

In this study, single-cell sequencing revealed clonal expansions of CD4+ and CD8+ T cells in murine and human alopecia areata, supporting the development of predictive models for human disease.

This study outlines treatment strategies for autoimmune alopecia areata, detailing that while mild cases may resolve on their own, severe cases often require intervention, with new JAK inhibitors like baricitinib and ritlecitinib emerging as promising treatments for those not responding to traditional therapies.

This case study reports a previously undescribed cause of drug-induced autoimmune hepatitis triggered by para-aminobenzoic acid (PABA), emphasizing the need for caution with this supplement.

Alopecia areata is linked to immune system differences, with specific biomarkers like CXCL9 and CXCL10 being key for diagnosis and potential treatment targets.

This case report illustrates that false-positive antibodies for Ehrlichia species may occur in patients with systemic lupus erythematosus, complicating diagnosis and treatment.

This case report describes a patient with autoimmune autonomic neuropathy associated with high-titer gAChR antibodies who developed selective pigmented hair loss during IV immunoglobulin treatment.

This review supports an autoimmune hypothesis for Satoyoshi syndrome, noting associations with autoantibodies and autoimmune diseases, and reports an observed improvement in most patients with corticosteroid or immunosuppressant treatments.

This study examined FAERS data and found an increasing trend in alopecia areata cases, with monoclonal antibodies most frequently linked to the condition.

This study found that anti-Ku-positive patients exhibit heterogeneous muscle features, primarily showing a myositis pattern with necrotizing fibers and vacuolar changes, and suggests autophagy may play a significant role in their pathogenesis.

In this paper, three APS patients were followed over time, showing that the diagnosis and course of autoimmune polyglandular syndrome can evolve, highlighting the need for careful monitoring and potential re-evaluation.

This article discusses various autoimmune diseases, including their symptoms and management, and reports no new clinical findings.

This article discusses autoimmune diseases, detailing their types, symptoms, and potential management strategies, without providing new clinical findings.

This study observed that patients with alopecia areata often have a T-cell receptor repertoire in skin lesions that suggests a specific antigen-driven immune response may be important in the disease's pathogenesis.

In this case report, a girl with autoimmune polyglandular syndrome type 1 experienced stabilized disease and reversal of alopecia universalis after treatment with glucocorticoids and methotrexate.

Autoimmune myopathy may be linked to hair loss and skin depigmentation.

In this case study, a 25-year-old presented with symptoms of lupus but tested negative for antinuclear antibodies, complicating diagnosis. The researchers emphasize that comprehensive diagnostic approaches, beyond ANA testing, are vital for effectively identifying and treating lupus nephritis to avoid serious outcomes.

In this study, plasma levels of MSH and cortisol in patients with alopecia areata did not show significant changes compared to healthy controls.

This study found that a novel IKZF1 mutation, p.L188V, is linked to juvenile-onset systemic lupus erythematosus and alters B-cell activation by disrupting normal DNA binding.