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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Estrogen therapy can reduce skin aging but has cancer risks.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Foals with Rhodococcus equi infection often have other health problems that lower their chances of survival.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

A woman's health issues were caused by arsenic poisoning from kelp supplements.

The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Artesunate is generally safe for severe malaria, but patients should be monitored for delayed anemia after treatment.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Some alternative treatments for hair loss might work, but more research is needed.