Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that dermoscopy of the axilla in patients with frontal fibrosing alopecia revealed significantly higher odds of brownish peripillary halos, suggesting a diagnostic clue for the condition in this region.

This study suggests that allergens like linalool found in personal care products may contribute to the pathobiology of frontal fibrosing alopecia by affecting immune responses and stem cell function in hair follicles.

This study reports no new clinical results but suggests a potential relationship between frontal fibrosing alopecia and cutaneous conditions such as rosacea, indicating a need for further research.

PRSS35 enzyme may help start skin tumors and could be a target for cancer treatment.

In this study, sensitization to ethylhexyl salicylate was found in 27.3% of patients with frontal fibrosing alopecia, suggesting it may be a potential contact allergen for this condition.

Targeting immune pathways like JAK/STAT may help treat frontal fibrosing alopecia.

This study identified the transcription factor Elf5 as a novel regulator of keratinocyte proliferation and differentiation in skin, with expression elevated in stem/progenitor cell populations, suggesting its potential role in determining cell fate during skin and hair development.

A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.

The study suggests hormonal factors may play a role in Frontal Fibrosing Alopecia and that treatments like oral antiandrogens and steroids could be beneficial.

This study found that eyelash loss, facial papules, and body hair involvement were linked to severe frontal fibrosing alopecia, and antiandrogens were the most effective treatment.

In a clinical phase I/IIa study, subcutaneous injections of the peptide FOL-005 increased hair growth by 8% and were safe for treating alopecia.

This study identifies a polygenic basis for atypical recurrent flank alopecia in Cesky Fousek dogs through genome-wide association analysis and gene expression profiling, highlighting several metabolic pathways involved in the condition.

In this study, inactivating the TAF4 subunit of transcription factor TFIID in mouse epidermis disrupted gene expression linked to skin and hair function, and increased tumor risk.

Oral dutasteride and topical pimecrolimus can safely and effectively treat Frontal Fibrosing Alopecia, leading to significant hair regrowth.

This study found that Egyptian women with frontal fibrosing alopecia had lower serum PPARγ levels and a higher occurrence of PPARG gene polymorphism compared to healthy controls, suggesting a potential role for PPARγ in the condition's development.

In this observational study, dutasteride treatment was associated with statistically significant stabilization of frontal fibrosing alopecia compared to other systemic therapies, with a dose-dependent effect observed across the frontal and bilateral temporal hairlines.

Certain drugs and supplements may contribute to hair loss in the frontal hairline in older women.

This study found that tofacitinib may be effective for treating pediatric rheumatic diseases, with especially promising results in patients with autoinflammatory diseases, arthritis and alopecia, and juvenile dermatomyositis.

This study found that ectopic expression of FGF5s in transgenic Chinese Merino sheep increased wool length and greasy fleece weight compared to non-transgenic controls.

This review covers the clinical presentation and challenges in treating frontal fibrosing alopecia in postmenopausal women and concludes that more research is needed to understand its etiology and develop effective treatments.

This study provides the first crystal structure of the human SRD5A2 enzyme, revealing key insights into its function and inhibition which may aid future drug development.

This article notes slow progression and spontaneous stabilization in untreated cases of a specific scarring alopecia and reports no new results; the authors call for randomized trials to confirm the treatment's benefit.

This review discusses frontal fibrosing alopecia in males and reports no new clinical results, indicating a broader demographic affected by this inflammatory disorder beyond postmenopausal women.

This study found that in Arabidopsis thaliana, the interaction between extracellular leucine-rich repeat extensins and the receptor-like kinase FERONIA helps control vacuolar expansion, crucial for cellular elongation.

This study found that certain circulating miRNAs in skin and plasma may serve as potential biomarkers for distinguishing frontal fibrosing alopecia from control cases, highlighting the need for further validation in larger cohorts.

This study found that FGF21 suppresses inflammation induced by C. acnes in both human skin cells and mouse models, suggesting potential use in acne treatment.

This study observed that frontal fibrosing alopecia is increasingly diagnosed in Italian Caucasian females, often showing premenopausal onset and eyebrow alopecia as an early sign.

This review discusses the enigmatic nature of frontal fibrosing alopecia and reports no clinical results; the authors stress the need for further research.