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Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Hair loss in androgenic alopecia may be linked to increased local androgen activities, but not to estrogen levels.

Balding scalps show different gene expressions affecting hair growth compared to non-balding scalps.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.

Lespedeza cuneata extract may help treat enlarged prostate.

A prostate cancer drug can lower the levels of a protein that the coronavirus uses to enter lung cells.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Dutasteride and finasteride affect different cell types differently.

TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.

Ketoconazole shampoo with finasteride improves hair density in men with hair loss.

Mutations in certain receptors can cause diseases and offer new treatment options.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

Androgen deprivation therapy might be better for preventing COVID-19 than treating it.

Methylation in specific gene region causes finasteride resistance in some BPH patients.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

A specific genetic deletion in goats affects cashmere yield and thickness.

Exemestane may protect bones by stimulating osteoblast growth through androgen-related pathways.

Mouse genital development depends on male or female hormones for specific features.

Testosterone's effects on COVID-19 are unclear and need more research.