64 citations
,
June 2020 in “PLoS ONE” This study found that red light exposure significantly enhanced the growth, phytochemical content, and therapeutic potential of Eclipta alba callus cultures compared to other multispectral light exposures.
63 citations
,
December 2002 in “Archives of Dermatology” This abstract contains no research results; it provides information about the JAMA Dermatology journal and its access options.
61 citations
,
May 2015 in “Planta” Certain fungi and bacteria help orchid seeds germinate and plants grow better.
59 citations
,
June 2022 in “Frontiers in medicine” This review discusses the complex causes and treatment challenges of chronic inflammatory skin diseases, emphasizing the need for biomarkers to predict treatment responses; it reports no new clinical results.
53 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.
49 citations
,
April 2015 in “Emerging Infectious Diseases” In this study, artesunate was confirmed as an effective treatment for severe malaria, but post-treatment hemolytic anemia occurred, although it was mostly mild and only one transfusion was needed.
47 citations
,
December 2020 in “Journal of the European Academy of Dermatology and Venereology” This article reviews the classification, diagnosis, and management of hair disorders, emphasizing the role of trichoscopy and early diagnosis for effective treatment but reports no new clinical findings.
46 citations
,
January 2015 in “Pediatric Rheumatology” This review highlights the importance of recognizing mucocutaneous lesions in diagnosing juvenile-onset systemic lupus erythematosus, noting that these lesions often improve with controlled lupus and can indicate disease activity.
44 citations
,
February 2021 in “Scientific Reports” This study found that specific mutations in the spike protein of SARS-CoV-2 may significantly alter its structure and affect how it binds to certain inhibitors, but experimental studies are needed to confirm potential clinical implications.
44 citations
,
April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
42 citations
,
March 2018 in “PLOS Biology” This study found that autophagy plays a novel role in human hair growth, with altered autophagic flux during hair development phases influencing hair follicle behavior in a preclinical model.
41 citations
,
August 1988 in “Journal of The American Academy of Dermatology” In this case report, a patient with subacute cutaneous lupus erythematosus and exfoliative erythroderma achieved complete remission with systemic corticosteroids and long-term hydroxychloroquine.
40 citations
,
July 2007 in “Dermatologic Therapy” This review discusses the pharmacologic properties, mechanisms, dosing options, and adverse effects of systemic glucocorticosteroids in dermatology, but reports no new findings.
39 citations
,
April 2020 in “IntechOpen eBooks” The authors describe drug repurposing as a promising strategy for finding new uses for existing drugs, noting it is efficient, cost-effective, and poses lower risks than traditional drug discovery processes, potentially aiding in the treatment of rare and difficult-to-treat diseases.
39 citations
,
September 2016 in “Expert Opinion on Drug Delivery” This review explores how colloidal drug delivery systems can enhance the stability, absorption, and bioavailability of phytochemicals, potentially rediscovering ancient compounds' therapeutic benefits and overcoming limitations like poor solubility and bioavailability.
39 citations
,
April 2011 in “Recent Patents on Drug Delivery & Formulation” This review discusses various applications of nanoemulsions in drug delivery and reports no new clinical results; it highlights the patents that cover these applications.
39 citations
,
July 2008 in “Dermatologic Therapy” This review provides a practical approach to diagnosing pseudopelade of Brocq and updates on treatment options but reports no new clinical results.
39 citations
,
October 2018 in “Lupus Science & Medicine” This article discusses various patterns of hair loss associated with lupus erythematosus, emphasizing the importance of identifying the specific type to aid in classifying systemic lupus erythematosus.
37 citations
,
September 2017 in “Reumatología Clínica” In this systematic review and meta-analysis, methotrexate and leflunomide were compared for treating rheumatoid arthritis, showing similar efficacy overall. Methotrexate reduced swollen joints more effectively, while leflunomide was associated with fewer gastrointestinal side effects but more frequent liver enzyme increases.
37 citations
,
August 2016 in “Clinical, Cosmetic and Investigational Dermatology” This article discusses central centrifugal cicatricial alopecia, highlighting its prevalence, potential genetic factors, and management challenges, but reports no new clinical conclusions and calls for further research.
37 citations
,
January 1997 in “Clinics in Dermatology” This study found that women with androgenetic alopecia and alopecia areata had significantly lower serum ferritin levels compared to women without hair loss.
35 citations
,
July 2007 in “Dermatologic clinics” This review discusses the causes and diagnostic process for facial hypermelanosis, emphasizing the need to rule out systemic disorders like Addison's disease; it reports no new clinical findings.
34 citations
,
April 2009 in “Expert Opinion on Pharmacotherapy” This review discusses evidence-based treatments for common hair loss forms, noting robust support for androgenetic alopecia therapies but limited long-term data and fewer high-quality studies for alopecia areata and cicatricial alopecias.
34 citations
,
August 2002 in “British Journal of Dermatology” This study observed that two patients treated with interferon α-2b and ribavirin for chronic hepatitis C experienced complete and reversible straightening of their natural curly hair, which recurred with treatment resumption.
33 citations
,
August 2024 in “Frontiers in Drug Discovery” In this article, the authors describe how drug repurposing, supported by large-scale data and artificial intelligence, can make drug discovery more cost-effective and expedient compared to traditional methods, despite certain regulatory challenges.
33 citations
,
January 2011 in “Elsevier eBooks” This article reviews the complexity and diverse manifestations of systemic lupus erythematosus, highlighting potential genetic, hormonal, and environmental factors in its pathogenesis without presenting new clinical findings.
32 citations
,
January 2021 in “Molecules” This review compiles studies on the antidiabetic potential of plants from the Middle East, particularly from the Asteraceae and Lamiaceae families, but reports no clinical results.
32 citations
,
August 2015 in “Anais Brasileiros de Dermatologia” This review discusses the side effects and diseases related to hairstyles and hair treatments among black women, highlighting the need for thorough examination by dermatologists, but reports no new clinical results.
32 citations
,
November 2011 in “International Journal of Dermatology” This article reviews central centrifugal cicatricial alopecia, focusing on its multifactorial etiology and challenges in clinical diagnosis, and calls for more research and better treatment options.
32 citations
,
September 1989 in “Medical Clinics of North America” This review describes the types of skin lesions associated with systemic lupus erythematosus, discussing their histopathological features, serologic associations, pathogenesis, and prognostic implications.