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Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Cyproterone acetate can cause rare shortness of breath in women.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Spironolactone is an effective and well-tolerated first-line treatment for hidradenitis suppurativa in women.

Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.