research A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity
Clascoterone is safe for the heart, even at high doses.
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research Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism
Diane 35 plus finasteride is more effective for treating hirsutism.
research Topical Use of Systemic Drugs in Dermatology: A Comprehensive Review
Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
research Spironolactone: An Anti-Androgenic and Anti-Hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19
Spironolactone might help protect against severe lung problems in COVID-19 patients.
research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Androgenic Modulation of Arterial Baroreceptor Dysfunction and Neuroinflammation in Endotoxic Male Rats
Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
research The Role of Dietary Supplements in Hair Loss Treatment: A Review of Evidence
Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.
research Hirsutism: Diagnosis and Treatment
The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.
research Pasikula (Turmeric Paste for Axilla) as a Herbal Armpit Hair Remover
PASIKULA, a turmeric-based hair removal product, successfully sold well and boosted turmeric's economic value.
research The Hair Tales of Women of Color in Northern Manhattan: A Qualitative Analysis
Women of color in Northern Manhattan view hair care as important to their identity and culture, and education on harmful chemicals in hair products is needed.
research Safety of Antiandrogens for the Treatment of Female Androgenetic Alopecia with Respect to Gynecologic Malignancies
Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.
research Therapeutic Effect of Finasteride Through Its Antiandrogenic and Antioxidant Role in a Propionic Acid-Induced Autism Model: Demonstrated by Behavioral Tests, Histological Findings and MR Spectroscopy
Finasteride may help treat autism by reducing inflammation and oxidative stress.
research Evaluation of Derma Genie-H001 as a Functional Cosmetic Ingredient for Hair Loss Improvement: Assessing Anti-Inflammatory, Antioxidative, Photoprotective, Antiandrogenic, and Hair Growth-Inductive Effects
Derma Genie™-H001 can help prevent hair loss and promote hair growth.
research Inhibitory Effects of Serenoa Repens on the Kinetics of Pig Prostatic Microsomal 5α-Reductase Activity
Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
research Effect of Carbamates on mRNA Encoding Lipid Enzymes in Hamster Flank Organs
Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.
research G-Proteins, Receptor Signal Transduction, and Growth Hormone Secretion
The document concludes that antiandrogenic drugs like cyproterone acetate and spironolactone are effective but not permanent treatments for skin-related androgenization in women.
research Antiandrogenic Progestins for Treatment of Signs of Androgenisation and Hormonal Contraception
Certain hormone medications can treat symptoms like acne and unwanted hair, regulate periods, and prevent pregnancy in women and teenage girls.
research Can We Halt Male Androgenetic Alopecia Progression Without Antiandrogenic Drugs?
Only anti-androgenic drugs likely halt AGA progression.
research Frontal Fibrosing Alopecia: A Review of 355 Cases in a Spanish Population
Hormonal imbalances may play a role in frontal fibrosing alopecia, and antiandrogenic drugs combined with steroids are currently the most effective treatment.
research 5α-Reductase Inhibitory Potential of Hibiscus Rosa Sinensis: Effective for the Management of Alopecia
Hibiscus rosa sinensis may help manage hair loss.
research Antiandrogenic Drugs: A Therapeutic Option for Frontal Fibrosing Alopecia Patients
Antiandrogenic drugs could be a good treatment option for frontal fibrosing alopecia.
research Bicalutamide: A Potential New Oral Antiandrogenic Drug for Female Pattern Hair Loss
Bicalutamide may be a promising alternative treatment for female pattern hair loss.
research Flutamide in the Treatment of Hirsutism
Flutamide effectively reduces hair growth in women with hirsutism and improves acne and seborrhea without side effects.
research Reduction of Diameter of Hair Shaft Among Women With Hirsutism
Aldactone effectively reduces hair thickness in women with excessive hair growth, both alone and with other treatments.
research Reduction of Diameter of Hair Shaft Among Women With Hirsutism
Spironolactone effectively makes hair shafts thinner in women with excessive hair growth.
research Treatment of Hirsutism with Spironolactone
Spironolactone is effective and safe for treating excessive facial hair in women.
research Uses of Spironolactone as an Antiandrogenic Drug
Spironolactone is effective and safe for treating hair loss, excessive hair growth, and acne.
research Steroid 5α-Reductase Inhibitors
New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
research Niosomal And Ethosomal Gels: A Comparative In Vitro And Ex Vivo Evaluation For Repurposing Of Spironolactone
Niosomes and ethosomes can effectively carry the drug spironolactone, potentially improving treatment for hair loss and reducing side effects.
research Antiandrogen Therapy of Acne, Hair Loss, and Hirsutism
Cyproterone acetate is an effective treatment for women with acne, hair loss, and excessive hair growth.