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Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Antidepressants called SSRIs can cause skin problems, bleeding risk, and other side effects.

Giving docetaxel weekly at 40 mg/m² is manageable and has low toxicity for cancer patients.

Trichohyalin is also found in the outer layers of normal human skin.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.

Cysteine helps maintain keratin production in skin cells even when iron is low.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Scalp hair follicle culture has limits for testing minoxidil's hair growth effects.

Allergic reactions to blood thinners are rare but can be serious, requiring careful management and alternative treatments.

Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.

Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.

bFGF, VEGF, and minoxidil decrease collagen production in hair cells, possibly affecting hair growth.

A mother and son both had ulcerative colitis and alopecia, suggesting a genetic link in autoimmune disorders and successful treatment with cyclosporine.

Platelet-rich plasma (PRP) treatment has been found effective in promoting hair growth for alopecia patients, with minimal side effects like temporary pain and redness.

Minoxidil may help prevent capsular opacification after cataract surgery.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.

Platelet-rich plasma is beneficial in various plastic surgery applications, but more research is needed to standardize its use.

Encapsulated Garcinia mangostana extract in cream penetrates skin better than other forms.

Thyroid receptor agonists may treat male pattern baldness without harmful side effects.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.

Mushroom-based scaffolds help heal skin wounds and regrow hair.

Trichoscopy helps quickly identify autoimmune diseases on the scalp but should be used with other standard tests.