research Involvement of the Bulge Region with Decreased Expression of Hair Follicle Stem Cell Markers in Senile Female Cases of Alopecia Areata
Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.
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research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research Adipose Tissue Transplant in Recurrent Folliculitis Decalvans
Fat tissue transplant may be an effective new treatment for severe, treatment-resistant hair loss from folliculitis decalvans.
research Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair
Fat cells in the skin help start healing and form important repair cells after injury.
research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia
The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
research Aqueous Extract of Asiasari Radix Inhibits Formalin-Induced Hyperalgesia via NMDA Receptors
Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.
research Minoxidil: A Comprehensive Review
Minoxidil effectively treats hair loss, especially androgenetic alopecia, but needs more research for better understanding.
research Signal Transducer and Activator of Transcription 5B Deficiency Due to a Novel Missense Mutation in the Coiled-Coil Domain
A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.
research Histopathological and Immunohistochemical Study of Trichoblastoma in the Rabbit
Trichoblastomas in rabbits are linked to uncontrolled embryonic hair growth and have distinct histological features.
research CD201+ Fascia Progenitors Choreograph Injury Repair
CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.
research Hormones
Hormones are crucial for regulating body functions and imbalances can lead to health issues.
research Association Between Alopecia Areata and Thyroid Dysfunction
People with Alopecia Areata often have thyroid problems like Hashimoto thyroiditis and hypothyroidism.
research Systemic Antifungals: Overview, Applications, and Costs
Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.
research Annotated Patent Selections
The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.
research Anticancer Drugs in Surface Waters
Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.
research Fgf9 From Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding
A protein from certain immune cells is key for new hair growth after skin injury in mice.
research The PDGF/PDGFR Pathway as a Drug Target
The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
research Cutaneous Lupus Erythematosus: A Review
Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
research Cutting Edge: Memory Regulatory T Cells Require IL-7 and Not IL-2 for Their Maintenance in Peripheral Tissues
Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.
research Targeting the Wnt Pathways for Therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
research Laminin-511 Is an Epithelial Message Promoting Dermal Papilla Development and Function During Early Hair Morphogenesis
Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
research Alopecia Areata Update
Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.
research HPLC-ESI-MSn Characterization of Phenolic Compounds, Terpenoid Saponins, and Other Minor Compounds in Bituminaria Bituminosa
Researchers found over 40 compounds in Bituminaria bituminosa, including many flavonoids and some with potential for medical and hair care uses.
research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1
Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
research Revising the Role of the Androgen Receptor in Breast Cancer
The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
research Beta-Caryophyllene Enhances Wound Healing Through Multiple Routes
Beta-caryophyllene helps improve wound healing in mice, especially in females.
research Specific Receptor Detection by a Functional Keratinocyte Growth Factor-Immunoglobulin Chimera
A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.
research The Role of Lymphocytes in the Development and Treatment of Alopecia Areata
Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
research Mechanisms of Hepatocyte Attachment to Keratin Biomaterials
Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.