89 citations
,
January 2015 in “Medical Clinics of North America” Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.
78 citations
,
October 2006 in “International Journal of Cosmetic Science” Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.
71 citations
,
November 2012 in “Expert Opinion on Drug Safety” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
65 citations
,
April 2002 in “Journal of Alternative and Complementary Medicine” Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.
64 citations
,
January 2015 in “BioMed Research International” Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.
43 citations
,
August 2016 in “International Journal of Nanomedicine” Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
40 citations
,
February 2010 in “Experimental Dermatology” The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.
31 citations
,
April 2015 in “Journal of The American Academy of Dermatology” Prostaglandin F2α analogs show promise for treating certain types of hair loss but need more research for other skin conditions.
30 citations
,
January 2000 in “Dermatologic Clinics” Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
20 citations
,
April 2005 in “Current Medicinal Chemistry” New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
18 citations
,
January 2009 in “Journal of Endocrinological Investigation” Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.
18 citations
,
July 2008 in “Current Oncology Reports” EGFR cancer drugs often cause a rash, which can lead to distress and isolation, but may also improve outcomes for some cancer patients. Current treatments for the rash are limited, but a compound called menadione shows promise.
15 citations
,
October 2010 in “Archives of Toxicology” A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.
11 citations
,
June 2022 in “Frontiers in immunology” New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
10 citations
,
June 2018 in “Aaps Pharmscitech” The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
9 citations
,
June 2019 in “Mycopathologia” Malassezia yeast linked to hair loss; ketoconazole helps treat it.
8 citations
,
October 1989 in “International Journal of Dermatology” Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
7 citations
,
January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
6 citations
,
October 1993 in “The journal of the Royal Society of Health” Children's hair loss has many causes and requires careful diagnosis and personalized treatment, including emotional support.
5 citations
,
August 2017 in “Current Opinion in Pediatrics” Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.
4 citations
,
April 2018 in “Journal of labelled compounds & radiopharmaceuticals” A new compound was effective for imaging prostate cancer in rats.
3 citations
,
November 2005 in “Women's health” Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.
1 citations
,
October 2018 in “InTech eBooks” The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.
1 citations
,
September 2017 Minoxidil helps stimulate hair growth and enlarge small follicles in common hair loss, but doesn't stop it, and its effects can be boosted when combined with finasteride.
1 citations
,
January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
April 2024 in “Academic dermatology” Dermatologists should carefully manage hair loss in cancer patients to improve their quality of life.
March 2024 in “Journal of medicinal plants studies” Hibiscus has medicinal benefits but can be toxic in high doses and is unsafe for pregnant women and infants.
January 2024 in “Deleted Journal” Essential oils may help hair health but lack strong scientific proof and can cause allergic reactions.
August 2023 in “Malaysian Journal of Medicine and Health Sciences/Malaysian journal of medicine and health sciences” Pueraria mirifica extract may help treat benign prostatic hyperplasia.