86 citations
,
July 2002 in “Clinical and Experimental Dermatology” This review discusses female pattern hair loss, emphasizing its complex causes and the limited treatment options available, and reports no new clinical results.
83 citations
,
May 1999 in “International Journal of Dermatology” Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.
81 citations
,
March 2009 in “Seminars in Cutaneous Medicine and Surgery” This review discusses the classifications, diagnostic methods, and treatment strategies for female pattern hair loss, but reports no clinical results.
81 citations
,
May 2007 in “Fertility and Sterility” This review discusses the safety of testosterone therapy for postmenopausal women and concludes that, aside from hirsutism and acne, it appears safe at physiological doses for several years, though more long-term studies are needed.
78 citations
,
December 2011 in “Clinical toxicology” This study describes a case series of nine patients experiencing symptoms of selenium toxicity after consuming a liquid dietary supplement with an excess amount of selenium.
77 citations
,
June 2017 in “Advances in Therapy” This review discusses recent advances and ongoing clinical trials in novel therapeutics for alopecia areata, despite the lack of current FDA-approved treatments for severe cases, and reports no new results.
77 citations
,
March 2001 in “Clinics in Dermatology” This article discusses treatment approaches for female pattern hair loss and concludes that available medical treatments are effective in reversing or stabilizing the condition in most cases of mild-to-moderate severity.
76 citations
,
July 2006 in “Veterinary Dermatology” In this pilot study, the researchers found that topical application of imiquimod 5% cream may significantly reduce equine sarcoid tumor size, with 80% of tumors showing more than 75% reduction.
75 citations
,
January 2011 in “Plastic and Reconstructive Surgery” This review discusses the use of dermal regeneration templates for treating burn injuries and other wounds, highlighting their effectiveness in reducing scars and aiding in regenerative processes, but reports no new clinical results.
74 citations
,
May 2016 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics” This review identifies shared interferon gamma-driven immune pathways in vitiligo and alopecia areata, revealing potential targets for new treatments, but reports no clinical results.
74 citations
,
April 2005 in “Dermatologic Clinics” This article reviews treatment options for male-pattern and female-pattern hair loss, telogen effluvium, and alopecia areata, but provides no new clinical results; algorithmic management approaches are included.
72 citations
,
January 2011 in “Current Pharmaceutical Design” This review discusses the potential role of steroid 5α-reductase inhibitors in treating neuropsychiatric disorders related to dopaminergic hyperreactivity but reports no new clinical results.
71 citations
,
January 2015 in “The Scientific World Journal” This review discusses the link between insulin resistance and skin conditions such as acanthosis nigricans and psoriasis, but provides no new clinical results.
68 citations
,
January 2007 in “Journal of Cosmetic and Laser Therapy” This review discusses laser/light treatments for pattern hair loss and reports no clinical validation of current devices; experts recommend physician evaluation to exclude other medical conditions.
68 citations
,
April 2002 in “Journal of Alternative and Complementary Medicine” This study suggests that botanical 5AR inhibitors like Serenoa repens and β-sitosterol may improve symptoms of androgenetic alopecia, with 60% of treated subjects showing improvement compared to placebo.
65 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews various types of primary cicatricial alopecias and emphasizes the importance of accurate diagnosis to improve management strategies, particularly detailing remaining lymphocytic forms and expanding on neutrophilic and mixed types.
65 citations
,
January 2011 in “Frontiers in Endocrinology” This review summarizes the role of neurosteroids in seizure disorders and highlights the potential of neurosteroid replacement therapy in epilepsy but presents no new clinical findings.
65 citations
,
April 2002 in “Journal of Alternative and Complementary Medicine” This study found that 60% of men with mild to moderate androgenetic alopecia showed improvement after treatment with botanically derived 5AR inhibitors, suggesting these compounds may be effective, though larger trials are needed.
64 citations
,
March 2017 in “Nature communications” This study identified 63 genetic loci associated with male-pattern baldness, uncovering genes and pathways that may help develop treatments and suggesting its connection to other human conditions.
64 citations
,
January 2004 in “American journal of clinical dermatology” This review describes various types of folliculitis based on their causes, clinical manifestations, and treatments, but reports no new clinical results.
62 citations
,
January 2003 in “Dermatology” This review suggests that androgenetic alopecia may be exacerbated by exposure to ultraviolet radiation and proposes considering it as a photoaggravated condition requiring photoprotection.
60 citations
,
April 2018 in “Clinical, cosmetic and investigational dermatology” This review discusses the causes and diagnosis of traction alopecia, emphasizing education for high-risk populations as there is currently no cure, and presents no new clinical findings.
60 citations
,
December 2015 in “Lasers in Medical Science” This review concluded that FDA-cleared low-level laser therapy devices are safe and effective for patients with male and female pattern hair loss who do not respond to or tolerate standard treatments.
59 citations
,
November 2015 in “International Journal of Cosmetic Science” This review considers oxidative stress effects on hair aging and emphasizes the need for dermatologists to recognize and treat factors affecting scalp and hair health, but it provides no new clinical findings.
59 citations
,
January 2010 in “Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review” This article reviews the medicinal properties of Semecarpus anacardium and its biologically active compounds, but it reports no new clinical results.
58 citations
,
March 2013 in “Human Reproduction Update” This review discusses various substances that can impact male fertility and stresses that products should be confirmed 'sperm-safe' through rigorous testing, not assumptions; it reports no new study results.
53 citations
,
April 2018 in “Journal of The American Academy of Dermatology” This article reviews therapy-related hair disorders in oncology patients, detailing underlying mechanisms and potential management strategies, but reports no new clinical findings.
53 citations
,
January 2017 in “Skin appendage disorders” This review discusses botulinum toxin's experimental off-label uses in dermatology, highlighting promising results but emphasizing the need for more clinical trials to confirm efficacy and safety.
52 citations
,
October 2004 in “Veterinary dermatology” This study found that 62% of neutered dogs with hair cycle arrest experienced partial to complete hair re-growth after melatonin treatment, but hair re-growth was not consistently linked to normal sex hormone levels.
52 citations
,
September 1996 in “Obstetrics & Gynecology” This study found that compliance rates for oral contraceptives are low and similar to those for other medical treatments, indicating a need for alternatives that require less daily adherence.