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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.

New compounds can block testosterone effects in rats and might help treat conditions like prostate cancer and acne.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Neurosteroids show promise for treating epilepsy and more research is needed.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

New ABCA12 gene mutations were linked to a skin condition with scaling and hair loss, and a treatment helped with hair loss in a related case.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Hormonal therapies are safe and effective for treating adult women's acne.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

AMH levels can't reliably tell the difference between LOCAH and all types of PCOS in women with excessive hair growth.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

After chemotherapy for a gestational trophoblastic tumor, normal pregnancy rates are possible, but there's a slightly higher risk of the tumor reoccurring in future pregnancies.

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.