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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The document explains how male reproductive hormones work and affect the body.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Many women with postadolescent acne also have hormonal imbalances and are at higher risk for metabolic issues.

Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

Bicalutamide may help treat female pattern hair loss.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Skin problems in PCOS, like excess hair, acne, and hair loss, may not always indicate high male hormone levels and need careful diagnosis for proper treatment.

The paper suggests that France's suspension of Diane-35 was hasty and could cause treatment issues and unintended pregnancies, recommending a re-evaluation and better patient information.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

Measuring plasma testosterone glucosiduronate is a reliable way to detect high male hormone levels in women.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Testosterone is crucial for development, growth, and various body functions in mammals.

Some ovarian tumors can cause masculinization, and it's important to check for various causes when this symptom is present.

The document concludes that androgenetic alopecia is common, has a genetic link, and can be diagnosed and treated with medications like finasteride and minoxidil.

Baicalin may help reduce excessive male hormone levels in PCOS.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.

Higher androstenedione levels in women with PCOS are linked to more severe symptoms.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.