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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Genetics and hormones cause hair loss; finasteride treats it safely.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

More research is needed to understand how testosterone is maintained in adult males.

The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

Most women with excessive hair growth have a hormonal cause.

All women with significant unwanted hair growth have hormonal imbalances, often from polycystic ovary syndrome.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.

The document explains how male reproductive hormones work and affect the body.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

An mFG score of 5 or more indicates above-normal hair growth in Southern Chinese women.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

The paper suggests that France's suspension of Diane-35 was hasty and could cause treatment issues and unintended pregnancies, recommending a re-evaluation and better patient information.

Some ovarian tumors can cause masculinization, and it's important to check for various causes when this symptom is present.

Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.

Human beard hair follicles change testosterone into other related hormones, but don't much change androstenedione into testosterone.

African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.