research Tolerance of Spironolactone in Acne and Hirsutism Treatment
Most patients tolerated spironolactone for acne and hirsutism despite common side effects like menstrual changes and breast tenderness.
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research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research Hormone Therapy for Transgender Patients
Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.
research 5α-Reduced Glucocorticoids: A Story of Natural Selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
research Liposomes with an Ethanol Fraction as an Application for Drug Delivery
Ethosomes improve drug delivery through the skin but may have side effects like irritation.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Autologous Platelet-Rich Plasma Therapy for Pattern Hair Loss: A Systematic Review
PRP therapy may increase hair density in pattern hair loss without serious side effects, but more research is needed.
research The Post-Finasteride Syndrome: Clinical Manifestation of Drug-Induced Epigenetics Due to Endocrine Disruption
Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.
research Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris
Topical therapies show promise for hair loss and acne treatment with minimal side effects.
research Topical Spironolactone in the Treatment of Ocular Graft-Versus-Host Disease
Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.
research Development and Evaluation of Finasteride Niosomes Targeting Hair Follicles for Androgenic Alopecia Management
Finasteride niosomes were developed and found to be effective in treating hair loss, with better results than commercial minoxidil, and could be a promising topical treatment for hair loss.
research Repurposing Steroidogenesis Inhibitors for the Therapy of Neuropsychiatric Disorders: Promises and Caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
research The Biology and Clinical Application of Systemic Glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research High-Dose Spironolactone for Acne in Patients with Polycystic Ovarian Syndrome: A Single-Institution Retrospective Study
Higher doses of spironolactone may improve acne in PCOS patients, but side effects are a concern.
research Using Platelet-Rich Plasma to Treat Hair Loss and Thinning
Platelet-rich plasma (PRP) injections effectively treat hair loss and thinning in both men and women, with high satisfaction and no major side effects.
research Clinical Pharmacokinetics and Pharmacodynamics of Finasteride
Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
research Efficacy and Safety of 5 Alpha-Reductase Inhibitor Monotherapy in Patients with Benign Prostatic Hyperplasia: A Meta-Analysis
5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.
research A Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Assess the Efficacy of a Nutritional Supplement in Female Androgenic Alopecia
The nutritional supplement Pilopeptan® WOMAN improved hair growth and thickness in women with hair loss.
research Strengthening Hair with Centella Asiatica: A Report of Clinical and Subjective Efficacy of a Local Treatment with a 0.5% Hair Lotion
A lotion with Centella asiatica extract reduced hair loss by 41% and increased hair strength without side effects.
research Arecaceae
Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.
research Formestane Preferred as Second-Line Therapy in Advanced Breast Cancer
Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.
research HairMax LaserComb Laser Phototherapy Device in the Treatment of Male Androgenetic Alopecia
HairMax LaserComb® effectively promotes hair growth and stops hair loss in males with androgenetic alopecia, with no serious side effects.
research Androgen Replacement in Women: A Commentary
Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.
research Cyclosporin: Applications in Small Animal Dermatology
Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
research Topical Ketoconazole: A Systematic Review of Current Dermatological Applications and Future Developments
Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Platelet-Rich Plasma and Its Utilities in Alopecia: A Systematic Review
Platelet-rich plasma (PRP) treatment has been found effective in promoting hair growth for alopecia patients, with minimal side effects like temporary pain and redness.
research Top Ten Clinical Pearls in the Treatment of Acne Vulgaris
Start acne treatment early to prevent scarring, consider antibiotic resistance, use maintenance therapy, and manage side effects carefully.
research Drug Safety Evaluation of Exemestane
Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
research Metformin or Thiazolidinedione Therapy in Polycystic Ovary Syndrome?
Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.