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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.

A woman's progressive hair loss was correctly diagnosed as a rare condition called fibrosing alopecia in a pattern distribution after initially being mistaken for a more common type.

Hydrangea serrata extract may promote hair growth and improve hair health.

Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.

Myo-inositol plus α-lactalbumin works better than myo-inositol alone for improving symptoms of PCOS.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.

Proxalutamide improved recovery, lowered death rates, and reduced hospital stay for COVID-19 patients.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Cross-sex hormone treatment in transsexual individuals helps understand how sex hormones affect diseases like heart disease and diabetes.

Pregnant women with PCOS have higher levels of Neurokinin B in the placenta, especially with female babies.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

The document concludes that diagnosing and treating hair loss is complex and requires understanding its psychological effects and underlying causes, while also calling for more research and new treatments.

Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.

Curcumin improved some metabolic factors in women with PCOS but did not affect cholesterol, insulin, or testosterone levels.

MitoQ may help treat hair loss by boosting hair growth pathways.

Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

Gut health affects skin diseases, and probiotics might help.