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The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.

Hormonal imbalances can cause skin and hair problems in women, and treatments that block male hormones can help.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.

Menopause affects hair and skin; more research needed for treatment.

ADSC-CE treatment safely increases hair density and thickness in androgenetic alopecia patients.

Spironolactone may help reduce hair loss in androgenic alopecia.

Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Rats had lasting erectile problems after stopping a certain medication.

Many patients on new leukemia drugs had mild to moderate skin reactions.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Coffee and tea might help hair growth in balding individuals, but side effects and alternative uses are being considered.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Melatonin improved mental health and metabolism in women with PCOS.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.

Low-dose flutamide improved hirsutism and satisfaction in women but had common side effects, causing some to stop treatment.

Early diagnosis and treatment of Hidradenitis Suppurativa are important to prevent serious physical and mental effects.

Many treatments for hair loss show potential, but more testing is needed to confirm their effectiveness. Only minoxidil for women and minoxidil and finasteride for men are FDA approved.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.