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Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

Researchers made two new compounds that could be used for medicine.

Androgens may worsen COVID-19 and hair loss could indicate the disease's severity.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Higher androgen levels do not cause baldness in men.

The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.

AGA progression involves increased lipid synthesis, electron transport, and hair follicle miniaturization.

AGA in children needs careful diagnosis due to low androgen levels and possible other causes.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.