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Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.

Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.

Testosterone may slow down wound healing and increase inflammation.

FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.

Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Certain drugs change freshwater snail shells to a "banana" shape.

Dosing time affects finasteride's effectiveness and safety in rats.

Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.

Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Finasteride safely lowers DHT levels without affecting testosterone.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.