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CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

The mouse models are effective for testing new hair loss treatments.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Androgen therapy might help some women with low libido, but it has risks and should be used carefully.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

ROS may affect hair loss related to hormones.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Thyroid receptor agonists may treat male pattern baldness without harmful side effects.